Treatment trials in young patients with chronic obstructive pulmonary disease and pre–chronic obstructive pulmonary disease patients: time to move forward

FJ Martinez, A Agusti, BR Celli, MLK Han… - American journal of …, 2022 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is the end result of a series of dynamic and
cumulative gene–environment interactions over a lifetime. The evolving understanding of …

[HTML][HTML] COVID-19 and COPD: a narrative review of the basic science and clinical outcomes

A Higham, A Mathioudakis, J Vestbo… - European respiratory …, 2020 - Eur Respiratory Soc
The 2019 coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in …

Blood eosinophils and chronic obstructive pulmonary disease: a global initiative for chronic obstructive lung disease science committee 2022 review

D Singh, A Agusti, FJ Martinez, A Papi… - American Journal of …, 2022 - atsjournals.org
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …

Systematic review on long-term adverse effects of inhaled corticosteroids in the treatment of COPD

M Miravitlles, A Auladell-Rispau… - European …, 2021 - Eur Respiratory Soc
Inhaled corticosteroids (ICSs) are indicated for the prevention of exacerbations in COPD;
however, a significant proportion of patients at low risk of exacerbations are treated with …

Impact of Pseudomonas aeruginosa Infection on Patients with Chronic Inflammatory Airway Diseases

M Garcia-Clemente, D de la Rosa, L Máiz… - Journal of clinical …, 2020 - mdpi.com
Pseudomonas aeruginosa (P. aeruginosa) is a ubiquitous and opportunistic microorganism
and is considered one of the most significant pathogens that produce chronic colonization …

Treatable traits in the NOVELTY study

A Agustí, E Rapsomaniki, R Beasley, R Hughes… - …, 2022 - Wiley Online Library
Background and objective Asthma and chronic obstructive pulmonary disease (COPD) are
two prevalent and complex diseases that require personalized management. Although a …

Blood eosinophil counts in clinical trials for chronic obstructive pulmonary disease

D Singh, M Bafadhel, CE Brightling… - American Journal of …, 2020 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a complex condition with pathophysiology
and clinical characteristics that vary in presence and severity between patients (1). This …

Inhaled corticosteroids in adults with non-cystic fibrosis bronchiectasis: from bench to bedside. A narrative review

MÁ Martínez-García, G Oscullo, A García-Ortega… - Drugs, 2022 - Springer
Due to their potent anti-inflammatory capacity (particularly in predominantly eosinophilic
inflammation) and immunosuppressive properties, inhaled corticosteroids (ICSs) are widely …

RIBRON: The Spanish online bronchiectasis registry. Characterization of the first 1912 patients

MA Martinez-García, C Villa, Y Dobarganes… - Archivos de …, 2021 - Elsevier
Abstract Introduction The SEPAR Spanish Bronchiectasis Registry (RIBRON) began as a
platform for the collection of longitudinal data on patients with this disease. The objective of …

Consensus document on the diagnosis and treatment of chronic bronchial infection in chronic obstructive pulmonary disease

D de la Rosa Carrillo, JL López-Campos… - Archivos de …, 2020 - Elsevier
Although the chronic presence of microorganisms in the airways of patients with stable
chronic obstructive pulmonary disease (COPD) confers a poor outcome, no …