Radiochemistry for positron emission tomography
Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …
PET molecular imaging in drug development: the imaging and chemistry perspective
Positron emission tomography with selective radioligands advances the drug discovery and
development process by revealing information about target engagement, proof of …
development process by revealing information about target engagement, proof of …
The chemical scaffold of theranostic radiopharmaceuticals: radionuclide, bifunctional chelator, and pharmacokinetics modifying linker
Therapeutic radiopharmaceuticals have been researched extensively in the last decade as
a result of the growing research interest in personalized medicine to improve diagnostic …
a result of the growing research interest in personalized medicine to improve diagnostic …
Radiochemistry with {Al18F} 2+: Current status and optimization perspectives for efficient radiofluorination by complexation
S Schmitt, E Moreau - Coordination Chemistry Reviews, 2023 - Elsevier
With the aim to efficiently develop and synthesize new radiotracers for PET imaging, and
their use for theranostic approaches, radiolabeling technics have not ceased to progress …
their use for theranostic approaches, radiolabeling technics have not ceased to progress …
Light‐Driven Radiochemistry with Fluorine‐18, Carbon‐11 and Zirconium‐89
This review discusses recent advances in light‐driven radiochemistry for three key isotopes:
fluorine‐18, carbon‐11, and zirconium‐89, and their applications in positron emission …
fluorine‐18, carbon‐11, and zirconium‐89, and their applications in positron emission …
Recent developments in carbon-11 chemistry and applications for first-in-human PET studies
A Pees, M Chassé, A Lindberg, N Vasdev - Molecules, 2023 - mdpi.com
Positron emission tomography (PET) is a molecular imaging technique that makes use of
radiolabelled molecules for in vivo evaluation. Carbon-11 is a frequently used radionuclide …
radiolabelled molecules for in vivo evaluation. Carbon-11 is a frequently used radionuclide …
PET radiotracers and fluorescent probes for imaging human carbonic anhydrase IX and XII in hypoxic tumors
Positron emission tomography (PET) and fluorescent imaging play a pivotal role in medical
diagnosis, biomedical oncologic research, and drug development process, which include …
diagnosis, biomedical oncologic research, and drug development process, which include …
Direct C–H Radiocyanation of Arenes via Organic Photoredox Catalysis
Innovative labeling methods to incorporate the short-lived positron emitter carbon-11 (11C)
into bioactive molecules are attractive for positron emission tomography (PET) tracer …
into bioactive molecules are attractive for positron emission tomography (PET) tracer …
Deciphering Drug Targets and Actions with Single-Cell and Spatial Resolution
Recent advances in chemical, molecular, and genetic approaches have provided us with an
unprecedented capacity to identify drug-target interactions across the whole proteome and …
unprecedented capacity to identify drug-target interactions across the whole proteome and …
[HTML][HTML] Advancement in production of radiotracers
SB Hansen, D Bender - Seminars in nuclear medicine, 2022 - Elsevier
After introduction of the first commercial combined PET and CT scanner in 2001, this
diagnostic tool quickly became a clinical success and was considered the fastest growing …
diagnostic tool quickly became a clinical success and was considered the fastest growing …