Communication in neural circuits: tools, opportunities, and challenges

TN Lerner, L Ye, K Deisseroth - Cell, 2016 - cell.com
Communication, the effective delivery of information, is fundamental to life across all scales
and species. Nervous systems (by necessity) may be most specifically adapted among …

Imaging synaptic density: the next holy grail of neuroscience?

ME Serrano, E Kim, MM Petrinovic… - Frontiers in …, 2022 - frontiersin.org
The brain is the central and most complex organ in the nervous system, comprising billions
of neurons that constantly communicate through trillions of connections called synapses …

DMD-based LED-illumination super-resolution and optical sectioning microscopy

D Dan, M Lei, B Yao, W Wang, M Winterhalder… - Scientific reports, 2013 - nature.com
Abstract Super-resolution three-dimensional (3D) optical microscopy has incomparable
advantages over other high-resolution microscopic technologies, such as electron …

Golgi-Cox staining step by step

S Zaqout, AM Kaindl - Frontiers in neuroanatomy, 2016 - frontiersin.org
Golgi staining remains a key method to study neuronal morphology in vivo. Since most
protocols delineating modifications of the original staining method lack details on critical …

Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

T Rubino, P Prini, F Piscitelli, E Zamberletti… - Neurobiology of …, 2015 - Elsevier
Current concepts suggest that exposure to THC during adolescence may act as a risk factor
for the development of psychiatric disorders later in life. However, the molecular …

Rearrangement of the dendritic morphology in limbic regions and altered exploratory behavior in a rat model of autism spectrum disorder

ME Bringas, FN Carvajal-Flores, TA López-Ramírez… - Neuroscience, 2013 - Elsevier
Valproic acid (VPA) is a blocker of histone deacetylase widely used to treat epilepsy, bipolar
disorders, and migraine; its administration during pregnancy increases the risk of autism …

Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia

ML Pershing, DM Bortz, A Pocivavsek, PJ Fredericks… - …, 2015 - Elsevier
The levels of kynurenic acid (KYNA), an endogenous negative modulator of alpha7 nicotinic
acetylcholine receptors (α7nAChRs), are elevated in the brains of patients with …

Golgi‐Cox staining of neuronal dendrites and dendritic spines with FD rapid GolgiStain™ kit

F Du - Current protocols in neuroscience, 2019 - Wiley Online Library
Abstract The Golgi‐Cox method has been one of the most effective techniques for studying
the morphology of neuronal dendrites and dendritic spines. However, the reliability and time …

Methods of dendritic spine detection: from Golgi to high-resolution optical imaging

JJ Mancuso, Y Chen, X Li, Z Xue, STC Wong - Neuroscience, 2013 - Elsevier
Dendritic spines, the bulbous protrusions that form the postsynaptic half of excitatory
synapses, are one of the most prominent features of neurons and have been imaged and …

High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain

MC Fonseca, BHS Araujo, CSB Dias, NL Archilha… - Scientific Reports, 2018 - nature.com
The assessment of neuronal number, spatial organization and connectivity is fundamental
for a complete understanding of brain function. However, the evaluation of the three …