Glycosylation as a regulator of site-specific metastasis

WE Bindeman, B Fingleton - Cancer and Metastasis Reviews, 2022 - Springer
Metastasis is considered to be responsible for 90% of cancer-related deaths. Although it is
clinically evident that metastatic patterns vary by primary tumor type, the molecular …

Microfluidic immunocapture of circulating pancreatic cells using parallel EpCAM and MUC1 capture: characterization, optimization and downstream analysis

FI Thege, TB Lannin, TN Saha, S Tsai, ML Kochman… - Lab on a Chip, 2014 - pubs.rsc.org
We have developed and optimized a microfluidic device platform for the capture and
analysis of circulating pancreatic cells (CPCs) and pancreatic circulating tumor cells (CTCs) …

[HTML][HTML] Role of Tau Protein in Neurodegenerative Diseases and Development of Its Targeted Drugs: A Literature Review

J Yang, W Zhi, L Wang - Molecules, 2024 - mdpi.com
Tau protein is a microtubule-associated protein that is widely distributed in the central
nervous system and maintains and regulates neuronal morphology and function. Tau …

Multifunctional gold nanorods for selective plasmonic photothermal therapy in pancreatic cancer cells using ultra-short pulse near-infrared laser irradiation

T Patino, U Mahajan, R Palankar, N Medvedev… - Nanoscale, 2015 - pubs.rsc.org
Gold nanorods (AuNRs) have attracted considerable attention in plasmonic photothermal
therapy for cancer treatment by exploiting their selective and localized heating effect due to …

Multi-armored allogeneic MUC1 CAR T cells enhance efficacy and safety in triple-negative breast cancer

P Erler, T Kurcon, H Cho, J Skinner, C Dixon… - Science …, 2024 - science.org
Solid tumors, such as triple-negative breast cancer (TNBC), are biologically complex due to
cellular heterogeneity, lack of tumor-specific antigens, and an immunosuppressive tumor …

[HTML][HTML] A comprehensive investigation to reveal the relationship between plasmacytoid dendritic cells and breast cancer by multiomics data analysis

S Tian, L Yan, L Fu, Z Zhang, J Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Plasmacytoid dendritic cells (pDC) are an essential immune microenvironment component.
They have been reported for crucial roles in linking the adaptive and immune systems …

Galectin-1 Influences Breast Cancer Cell Adhesion to E-selectin Via Ligand Intermediaries

NM Reynolds, A Mohammadalipour, CR Hall… - Cellular and Molecular …, 2018 - Springer
Introduction Invasion of other tissues during bloodborne metastasis in part requires
adhesion of cancer cells to vascular endothelium by specific fluid shear-dependent receptor …

N-(3-hydroxymethyl-β-carboline-1-yl-ethyl- 2-yl)-l-Phe: development toward a nanoscaled antitumor drug capable of treating complicated thrombosis and …

J Wu, M Zhao, Y Wang, Y Wang, H Zhu… - Drug Design …, 2017 - Taylor & Francis
It is well documented that the surfaces of cancer cells, activated platelets and inflammatory
cells are rich in P-selectin. N-(3-hydroxymethyl-β-carboline-1-yl-ethyl-2-yl)-l-Phe (HMCEF) is …

Development of a Lectin Binding Assay for Mucin-Type O-Glycosylated Serum Proteins: Identification of Potential Biomarkers for Screening of Breast Cancer

LC Siang - 2017 - search.proquest.com
Mucin-type O-glycosylated proteins are known to be related to many pathological diseases,
especially malignancy. Mucins such as CA 27.29, CA 125 and CA 19-9 have been actively …

[图书][B] An Investigation into the Effects of Galectin and Mac-2 Binding Protein on E-selectin Interactions in Cancer

NM Reynolds - 2020 - search.proquest.com
Galectins and Mac-2 binding protein (Mac-2BP) are some of the most ubiquitous proteins in
the immune system life cycle, aiding in regulation of inflammation, recruitment and adhesion …