Clinical and molecular aspects of lead toxicity: An update

P Mitra, S Sharma, P Purohit… - Critical reviews in clinical …, 2017 - Taylor & Francis
Lead toxicity is a major public health issue in developed and developing countries. Both
acute and chronic lead exposure has the potential to cause many deleterious systematic …

A critical review on lead removal from industrial wastewater: Recent advances and future outlook

V Kumar, SK Dwivedi, S Oh - Journal of Water Process Engineering, 2022 - Elsevier
Lead pollution has taken immense consideration of the industrialists, environmentalists,
policymakers and health workers due to its public health concerns. The wastewater …

METTL3-mediated m6A modification is required for cerebellar development

CX Wang, GS Cui, X Liu, K Xu, M Wang, XX Zhang… - PLoS …, 2018 - journals.plos.org
N 6-methyladenosine (m6A) RNA methylation is the most abundant modification on mRNAs
and plays important roles in various biological processes. The formation of m6A is catalyzed …

Neurodevelopmental disorders—high-resolution rethinking of disease modeling

K Khodosevich, CM Sellgren - Molecular Psychiatry, 2023 - nature.com
Neurodevelopmental disorders arise due to various risk factors that can perturb different
stages of brain development, and a combinatorial impact of these risk factors programs the …

Beyond cortex: The evolution of the human brain.

R Chin, SWC Chang, AJ Holmes - Psychological Review, 2023 - psycnet.apa.org
Human evolution has been marked by a striking increase in total brain volume relative to
body size. While a prominent and characteristic feature of this volumetric shift has been the …

Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury

Y Rong, C Ji, Z Wang, X Ge, J Wang, W Ye… - Journal of …, 2021 - Springer
Background Spinal cord injury (SCI) is a severe traumatic disease which causes high
disability and mortality rates. The molecular pathological features after spinal cord injury …

Developmental cell death in the cerebral cortex

FK Wong, O Marín - Annual review of cell and developmental …, 2019 - annualreviews.org
In spite of the high metabolic cost of cellular production, the brain contains only a fraction of
the neurons generated during embryonic development. In the rodent cerebral cortex, a first …

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins

M Zhang, D Chen, J Xia, W Han, X Cui… - Genes & …, 2017 - genesdev.cshlp.org
Despite extensive studies on mammalian neurogenesis, its post-transcriptional regulation
remains under-explored. Here we report that neural-specific inactivation of two murine post …

[HTML][HTML] More than mortar: glia as architects of nervous system development and disease

I Lago-Baldaia, VM Fernandes… - Frontiers in Cell and …, 2020 - frontiersin.org
Glial cells are an essential component of the nervous system of vertebrates and
invertebrates. In the human brain, glia are as numerous as neurons, yet the importance of …

Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4

S Ohlig, S Clavreul, M Thorwirth, T Simon‐Ebert… - The EMBO …, 2021 - embopress.org
Astrocytes regulate brain‐wide functions and also show region‐specific differences, but little
is known about how general and region‐specific functions are aligned at the single‐cell …