Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

Hepatocellular carcinoma (HCC) is one of the most lethal malignancies, and is also the
fourth most common cancer worldwide with around 700,000 new cases each year …

Summary β-catenin is upregulated in many human cancers and considered to be an
oncogene. Hepatocellular carcinoma (HCC) is one of the most prevalent human …

With an estimate of 350 million people chronically infected with the hepatitis B virus (HBV)
worldwide, it is critically important to understand how persistent HBV infection is maintained …

Despite recent advances in the understanding of the biologic basis of hepatocellular
carcinoma (HCC) development, the clinical management of the disease remains a major …

Chronic hepatitis B virus (HBV) infection is a major global cause of hepatocellular carcinoma
(HCC). Individuals who are chronic carriers have a greater than 100‐fold increased relative …

Hepatocellular carcinoma (HCC) is one of the most fatal human malignancies, but the
molecular mechanisms of hepatocarcinogenesis remain unclear. Although p53 mutations …

The hepatitis B virus X protein (HBx) plays essential roles in viral replication and the
generation of hepatocellular carcinoma. In spite of a large number of suggestive cellular …

Abstract Hepatitis B Virus (HBV) infection is one of the major causes of hepatocellular
carcinoma (HCC). X protein (HBx) has been suspected to be oncogenic, although the …

Chronic hepatitis B virus (HBV) infection is a complex clinical entity frequently associated
with cirrhosis and hepatocellular carcinoma (HCC). The persistence of HBV genomes in the …