Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

Therapeutic cancer vaccines have undergone a resurgence in the past decade. A better
understanding of the breadth of tumour-associated antigens, the native immune response …

Progress in the field of precision medicine has changed the landscape of cancer therapy.
Precision medicine is propelled by technologies that enable molecular profiling, genomic …

Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …

Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

An effective tumor vaccine vector that can rapidly display neoantigens is urgently needed.
Outer membrane vesicles (OMVs) can strongly activate the innate immune system and are …

The therapeutic effect of highly malignant triple negative breast cancer (TNBC) is negatively
affected by the formation of tumor cell resistant clone and the severe toxicity of …

Cancer metastases and recurrence after surgical resection remain an important cause of
treatment failure. Here we demonstrate a general strategy to fabricate personalized …

A major challenge in cancer vaccine therapy is the efficient delivery of antigens and
adjuvants to stimulate a controlled yet robust tumour-specific T-cell response. Here, we …

DNA derived from chemotherapeutics-killed tumor cells is one of the most important damage-
associated molecular patterns that can activate the cGAS-STING (cyclic GMP-AMP synthase …