[HTML][HTML] The potential benefits of polyphenols for corneal diseases

J Feng, Y Zhang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The cornea functions as the primary barrier of the ocular surface, regulating temperature and
humidity while providing protection against oxidative stress, harmful stimuli and pathogenic …

Evolution of therapeutic strategy based on oxidant-antioxidant balance for Fuchs endothelial corneal dystrophy

Y Wu, Y Liu, Y Feng, X Li, Z Lu, H Gu, W Li, LJ Hill… - The Ocular Surface, 2024 - Elsevier
Fuchs endothelial corneal dystrophy (FECD) stands as the most prevalent primary corneal
endothelial dystrophy worldwide, posing a significant risk to corneal homeostasis and clarity …

Delivery of curcumin by fucoidan-coated mesoporous silica nanoparticles: Fabrication, characterization, and in vitro release performance

X Zhang, Y Zhu, L Fan, J Ling, LY Yang, N Wang… - International Journal of …, 2022 - Elsevier
Mesoporous silica nanoparticles (MSN) are effective drug delivery carriers because of their
adjustable large pore size and high porosity. In this study, complex nanoparticles containing …

Faster and protective wound healing mechanistic of para‐coumaric acid loaded liver ECM scaffold cross‐linked with acellular marine kelp

A Arin, MS Rahaman, U Farwa… - Advanced Functional …, 2023 - Wiley Online Library
Decellularized liver‐derived extracellular matrix is a unique combination of a complex milieu
of growth factors and proteins that stimulate biochemical, physical, and mechanical cues to …

Highly effective corneal permeability of reactive oxygen species-responsive nano-formulation encapsulated cyclosporine a for dry eye management

D Yang, Y Han, Y Wang, Y Pan, L Zheng, Z Liu… - Chemical Engineering …, 2023 - Elsevier
Dry eye disease (DED) has become a globally recognized public health problem with
complex pathogenesis. Recent studies showed that oxidative stress damage and its induced …

[HTML][HTML] TCF4 trinucleotide repeat expansions and UV irradiation increase susceptibility to ferroptosis in Fuchs endothelial corneal dystrophy

S Saha, JM Skeie, GA Schmidt, T Eggleston… - Redox biology, 2024 - Elsevier
Fuchs endothelial corneal dystrophy (FECD), the leading indication for corneal
transplantation in the US, causes loss of corneal endothelial cells (CECs) and corneal …

The role of regulated necrosis in inflammation and ocular surface diseases

XX Guo, Q Pu, JJ Hu, XJ Chang, AL Li, XY Li - Experimental Eye Research, 2023 - Elsevier
In recent decades, numerous types of regulated cell death have been identified, including
pyroptosis, ferroptosis and necroptosis. Regulated necrosis is characterized by a series of …

Nutrient capsules maintain tear film homeostasis for human corneal lenticule transplantation

J Zhao, Z Zhang, F Xia, G Li, Q Saiding, L Xiang… - Chemical Engineering …, 2022 - Elsevier
Corneal lenticule transplantation can be applied in the correction of refractive errors and
various corneal diseases. However, current techniques to preserve cornea are limited due to …

Fusogenic liposome-coated nanoparticles for rapid internalization into donor corneal endothelial tissue to enable prophylaxis before transplantation

MY Thanuja, SS Tellakula, SV Suryavanshi… - Nanoscale …, 2023 - pubs.rsc.org
Cold stress (hypothermia) during storage and cytokine stress due to acute allograft rejection
adversely affect the donor corneal endothelium in the short term. Pharmacological pre …

A novel osmoprotective liposomal formulation from synthetic phospholipids to reduce in vitro hyperosmolar stress in dry eye treatments

MA Gonzalez Cela Casamayor… - Journal of Liposome …, 2023 - Taylor & Francis
Dry eye disease (DED) is a worldwide, multifactorial disease mainly caused by a deficit in
tear production or increased tear evaporation with an increase in tear osmolarity and …