Abstract AlphaFold2 (AF2) is an artificial intelligence (AI) system developed by DeepMind
that can predict three-dimensional (3D) structures of proteins from amino acid sequences …

Z-RNA is a higher-energy, left-handed conformation of RNA, whose function has remained
elusive. A growing body of work alludes to regulatory roles for Z-RNA in the immune …

Alternative non‐B‐DNA conformations formed under physiological conditions by sequences
called flipons include left‐handed Z‐DNA, three‐stranded triplexes, and four‐stranded i …

Peste des petits ruminants (PPR), a disease of socioeconomic importance has been a
serious threat to small ruminants. The causative agent of this disease is PPR virus (PPRV) …

Bioinformatic analyses have predicted that orbiviruses encode an additional, small non-
structural protein (NS5) from a secondary open reading frame on genome segment 10 …

Proteins, as the primary executors of physiological activity, serve as a key factor in disease
diagnosis and treatment. Research into their structures, functions, and interactions is …

The dynamic processes operating on genomic DNA, such as gene expression and cellular
division, lead inexorably to topological challenges in the form of entanglements, catenanes …

Z-nucleic acid structures play vital roles in cellular processes and have implications in innate
immunity due to their recognition by Zα domains containing proteins (Z-DNA/Z-RNA binding …

The discovery of a reversible transition in the helical sense of a double-helical DNA was
initiated by the first synthesis in 1967 of the alternating sequence poly [d (GC)]. In 1968 …

The self-complementary ld (CGCGCG) 2 purine/pyrimidine hexanucleotide was crystallized
in complex with the polyamine cadaverine and potassium cations. Since the oligonucleotide …