Single-cell manipulation and analysis is critical to the study of many fundamental biological
processes and uncovering cellular heterogeneity, and presents the potential for extremely …

Prostate cancer (PCa) is a prevalent malignancy that occurs primarily in old males. Prostate
tumors in different patients manifest significant inter-patient heterogeneity with respect to …

Circulating tumor cells (CTCs) are important biomarkers of liquid biopsy. The number and
heterogeneity of CTCs play an important role in cancer diagnosis and personalized …

Endothelial cells (ECs) constitute the inner lining of vascular beds in mammals and are
crucial for homeostatic regulation of blood vessel physiology, but also play a key role in …

Epithelial-mesenchymal transition (EMT) as a trans-differentiation program and a key
process in tumor progression is linked positively with increased expansion of cancer stem …

In recent years, advancements in single-cell and spatial transcriptomics, which are highly
regarded developments in the current era, particularly the emerging integration of single-cell …

Effective isolation and in-depth analysis of Circulating Tumour Cells (CTCs) are greatly
needed in diagnosis, prognosis and monitoring of the therapeutic response of cancer …

Liquid biopsy, a noninvasive technique to obtain tumor information from body fluids, is an
emerging technology for cancer diagnosis, prognosis, and monitoring, providing crucial …

The level of circulating tumor cells (CTCs) in blood is a predictor of metastatic cancer
progress, serving as an important biomarker for cancer diagnosis, prognosis, and therapy …

While cellular metabolism was proposed to be a driving factor of the activation and
differentiation of B cells and the function of the resulting antibody-secreting cells (ASCs), the …