Consciousness among delta waves: a paradox?
A common observation in EEG research is that consciousness vanishes with the
appearance of delta (1–4 Hz) waves, particularly when those waves are high amplitude …
appearance of delta (1–4 Hz) waves, particularly when those waves are high amplitude …
Consciousness and complexity: a consilience of evidence
Over the last years, a surge of empirical studies converged on complexity-related measures
as reliable markers of consciousness across many different conditions, such as sleep …
as reliable markers of consciousness across many different conditions, such as sleep …
A comprehensive atlas of E3 ubiquitin ligase mutations in neurological disorders
AJ George, YC Hoffiz, AJ Charles, Y Zhu… - Frontiers in …, 2018 - frontiersin.org
Protein ubiquitination is a posttranslational modification that plays an integral part in
mediating diverse cellular functions. The process of protein ubiquitination requires an …
mediating diverse cellular functions. The process of protein ubiquitination requires an …
Potassium channel dysfunction in human neuronal models of Angelman syndrome
Disruptions in the ubiquitin protein ligase E3A (UBE3A) gene cause Angelman syndrome
(AS). Whereas AS model mice have associated synaptic dysfunction and altered plasticity …
(AS). Whereas AS model mice have associated synaptic dysfunction and altered plasticity …
[HTML][HTML] Level of consciousness is dissociable from electroencephalographic measures of cortical connectivity, slow oscillations, and complexity
Leading neuroscientific theories posit a central role for the functional integration of cortical
areas in conscious states. Considerable evidence supporting this hypothesis is based on …
areas in conscious states. Considerable evidence supporting this hypothesis is based on …
Reduced prefrontal synaptic connectivity and disturbed oscillatory population dynamics in the CNTNAP2 model of autism
Loss-of-function mutations in CNTNAP2 cause a syndromic form of autism spectrum
disorder in humans and produce social deficits, repetitive behaviors, and seizures in mice …
disorder in humans and produce social deficits, repetitive behaviors, and seizures in mice …
[HTML][HTML] Multielectrode array analysis of EEG biomarkers in a mouse model of Fragile X Syndrome
Abstract Fragile X Syndrome (FXS) is a leading known genetic cause of intellectual disability
with symptoms that include increased anxiety and social and sensory processing deficits …
with symptoms that include increased anxiety and social and sensory processing deficits …
[HTML][HTML] Angelman syndrome: from mouse models to therapy
DC Rotaru, EJ Mientjes, Y Elgersma - Neuroscience, 2020 - Elsevier
The UBE3A gene is part of the chromosome 15q11-q13 region that is frequently deleted or
duplicated, leading to several neurodevelopmental disorders (NDD). Angelman syndrome …
duplicated, leading to several neurodevelopmental disorders (NDD). Angelman syndrome …
[HTML][HTML] Electrophysiological phenotype in Angelman syndrome differs between genotypes
J Frohlich, MT Miller, LM Bird, P Garces, H Purtell… - Biological …, 2019 - Elsevier
Background Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by
either disruptions of the gene UBE3A or deletion of chromosome 15 at 15q11-q13, which …
either disruptions of the gene UBE3A or deletion of chromosome 15 at 15q11-q13, which …
Functional rescue in an Angelman syndrome model following treatment with lentivector transduced hematopoietic stem cells
A Adhikari, NA Copping, J Beegle… - Human molecular …, 2021 - academic.oup.com
Angelman syndrome (AS) is a rare neurodevelopmental disorder characterized by impaired
communication skills, ataxia, motor and balance deficits, intellectual disabilities, and …
communication skills, ataxia, motor and balance deficits, intellectual disabilities, and …