Background Anti-angiogenic therapy represents a promising strategy for non-small-cell lung
cancer (NSCLC) but its application in lung squamous cell carcinoma (SQC) is limited due to …

Abstract Angiotensin‐converting enzyme 2 (ACE2) has been identified as the functional
receptor of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and a target for …

(1) Background: Emergence of methods interrogating gene expression at high throughput
gave birth to quantitative transcriptomics, but also posed a question of inter-comparison of …

Background Pancreatic carcinoma (PC) is one of the most aggressive cancers affecting
human health. It is essential to identify candidate biomarkers for the diagnosis and …

Lactic acidosis has been reported in solid tumor microenvironment (TME) including
glioblastoma (GBM). In TME, several signaling molecules, growth factors and metabolites …

The complex and interactive effects of genotype (G), environment (E), and management (M)
can be a barrier to the development of sound agronomic recommendations. We hypothesize …

Multipotent stromal cells are considered attractive sources for cell therapy and tissue
engineering. Despite numerous experimental and clinical studies, broad application of …

The tumor microenvironment (TME) plays a pivotal role in establishing malignancy, and it is
associated with high glycolytic metabolism and lactate release through monocarboxylate …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death due to its
early recurrence and widespread metastatic potential. Accumulating studies have reported …

Hepatocellular carcinomas (HCCs) exhibit a diversity of molecular phenotypes, raising
major challenges in clinical management. HCCs detected by surveillance programs at an …