Concise review: parthenote stem cells for regenerative medicine: genetic, epigenetic, and developmental features
B Daughtry, S Mitalipov - Stem cells translational medicine, 2014 - academic.oup.com
Embryonic stem cells (ESCs) have the potential to provide unlimited cells and tissues for
regenerative medicine. ESCs derived from fertilized embryos, however, will most likely be …
regenerative medicine. ESCs derived from fertilized embryos, however, will most likely be …
Haploid mouse embryonic stem cells: rapid genetic screening and germline transmission
A Wutz - Annual review of cell and developmental biology, 2014 - annualreviews.org
Most animal genomes are diploid, and mammalian development depends on specific
adaptations that have evolved secondary to diploidy. Genomic imprinting and dosage …
adaptations that have evolved secondary to diploidy. Genomic imprinting and dosage …
[HTML][HTML] Association of telomere length with authentic pluripotency of ES/iPS cells
Telomerase and telomeres are important for indefinite replication of stem cells. Recently,
telomeres of somatic cells were found to be reprogrammed to elongate in induced …
telomeres of somatic cells were found to be reprogrammed to elongate in induced …
[HTML][HTML] LncRNA Snhg1, a non-degradable sponge for miR-338, promotes expression of proto-oncogene CST3 in primary esophageal cancer cells
Y Yan, Q Fan, L Wang, Y Zhou, J Li, K Zhou - Oncotarget, 2017 - ncbi.nlm.nih.gov
Competing endogenous RNA (ceRNA) is a newly proposed mechanism that describes a
crosstalk among lncRNAs, mRNAs and their shared miRNAs. In this study, the role of miR …
crosstalk among lncRNAs, mRNAs and their shared miRNAs. In this study, the role of miR …
[HTML][HTML] Parthenogenetic stem cells for tissue-engineered heart repair
M Didié, P Christalla, M Rubart… - The Journal of …, 2013 - Am Soc Clin Investig
Cardiac muscle restitution, or true regeneration, is an unmet need in the treatment of
myocardial infarction (MI), prompting a decade of study with stem cells of many kinds …
myocardial infarction (MI), prompting a decade of study with stem cells of many kinds …
[HTML][HTML] Tet enzymes regulate telomere maintenance and chromosomal stability of mouse ESCs
Ten-eleven translocation (Tet) family proteins convert 5-methylcytosine to 5-
hydroxymethylcytosine. We show that mouse embryonic stem cells (ESCs) depleted of Tet1 …
hydroxymethylcytosine. We show that mouse embryonic stem cells (ESCs) depleted of Tet1 …
Germline potential of parthenogenetic haploid mouse embryonic stem cells
Haploid embryonic stem cells (ESCs) have recently been derived from parthenogenetic
mouse embryos and offer new possibilities for genetic screens. The ability of haploid ESCs …
mouse embryos and offer new possibilities for genetic screens. The ability of haploid ESCs …
[HTML][HTML] Feeders facilitate telomere maintenance and chromosomal stability of embryonic stem cells
Feeder cells like mouse embryonic fibroblasts (MEFs) have been widely applied for culture
of pluripotent stem cells, but their roles remain elusive. Noticeably, ESCs cultured on the …
of pluripotent stem cells, but their roles remain elusive. Noticeably, ESCs cultured on the …
Generation of developmentally competent oocytes and fertile mice from parthenogenetic embryonic stem cells
Parthenogenetic embryos, created by activation and diploidization of oocytes, arrest at mid-
gestation for defective paternal imprints, which impair placental development. Also, viable …
gestation for defective paternal imprints, which impair placental development. Also, viable …
[HTML][HTML] Roles for Tbx3 in regulation of two-cell state and telomere elongation in mouse ES cells
Mouse embryonic stem (ES) cell cultures exhibit heterogeneity and recently are discovered
to sporadically enter the 2-cell (2C)-embryo state, critical for ES potency. Zscan4 could mark …
to sporadically enter the 2-cell (2C)-embryo state, critical for ES potency. Zscan4 could mark …