Melatonin as an antioxidant: under promises but over delivers

RJ Reiter, JC Mayo, DX Tan, RM Sainz… - Journal of pineal …, 2016 - Wiley Online Library
Melatonin is uncommonly effective in reducing oxidative stress under a remarkably large
number of circumstances. It achieves this action via a variety of means: direct detoxification …

[HTML][HTML] The main molecular mechanisms underlying methamphetamine-induced neurotoxicity and implications for pharmacological treatment

X Yang, Y Wang, Q Li, Y Zhong, L Chen… - Frontiers in molecular …, 2018 - frontiersin.org
Methamphetamine (METH) is a popular new-type psychostimulant drug with complicated
neurotoxicity. In spite of mounting evidence on METH-induced damage of neural cell, the …

Mechanisms of melatonin in alleviating Alzheimer's disease

M Shukla, P Govitrapong, P Boontem… - Current …, 2017 - ingentaconnect.com
Alzheimer's disease (AD) is a chronic, progressive and prevalent neurodegenerative
disease characterized by the loss of higher cognitive functions and an associated loss of …

[HTML][HTML] Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm

RJ Reiter, R Sharma, MS Cucielo, DX Tan… - Cellular and Molecular …, 2023 - Springer
The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …

Methamphetamine use causes cognitive impairment and altered decision-making

H Mizoguchi, K Yamada - Neurochemistry international, 2019 - Elsevier
Methamphetamine is a widely abused psychostimulant. It reverses transport through the
dopamine transporter, thereby increasing the extracellular level of dopamine in the brain …

Increasing Nrf2 activity as a treatment approach in neuropsychiatry

G Morris, AJ Walker, K Walder, M Berk, W Marx… - Molecular …, 2021 - Springer
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor encoded by NFE2L2.
Under oxidative stress, Nrf2 does not undergo its normal cytoplasmic degradation but …

Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4/MyD88/NFκB signaling …

T Lwin, JL Yang, S Ngampramuan, K Viwatpinyo… - Progress in Neuro …, 2021 - Elsevier
Methamphetamine (METH) is a highly addictive psychostimulant that causes significant
health issues due to high prevalence of its illegal use. Chronic use of METH is associated …

Melatonin reverts methamphetamine-induced learning and memory impairments and hippocampal alterations in mice

N Veschsanit, JL Yang, S Ngampramuan, K Viwatpinyo… - Life sciences, 2021 - Elsevier
Aims Methamphetamine (METH) has become a major public health problem because of its
abuse and profound neurotoxic effects, causing alterations in brain structure and function …

Melatonin protects against methamphetamine-induced Alzheimer's disease-like pathological changes in rat hippocampus

P Panmak, C Nopparat, K Permpoonpattana… - Neurochemistry …, 2021 - Elsevier
Methamphetamine (METH) is a psychostimulant drug of abuse. METH use is associated with
cognitive impairments and neurochemical abnormalities comparable to pathological …

Sleep and hippocampal neurogenesis: implications for Alzheimer's disease

BA Kent, RE Mistlberger - Frontiers in neuroendocrinology, 2017 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia and currently there are no
effective disease-modifying treatments available. Hallmark symptoms of AD include …