Harnessing graft-versus-malignancy: non-myeloablative preparative regimens for allogeneic haematopoietic transplantation, an evolving strategy for adoptive …

R Champlin, I Khouri, A Shimoni… - British journal of …, 2000 - search.ebscohost.com
Examines the association of the therapeutic benefit of allogeneic bone marrow
transplantation with immune-mediated graft-versus-malignancy effect. Information on graft …

Graft-versus-host disease after donor leukocyte infusions: presentation and management

NV Frey, DL Porter - Best practice & research Clinical haematology, 2008 - Elsevier
Donor lymphocyte infusion (DLI) is used after both myeloablative and non-myeloablative
stem-cell transplantation to treat and prevent relapse, to establish full donor chimerism, and …

Donor-derived CMV-specific T cells reduce the requirement for CMV-directed pharmacotherapy after allogeneic stem cell transplantation

E Blyth, L Clancy, R Simms, CKK Ma… - Blood, The Journal …, 2013 - ashpublications.org
We investigated the use of adoptively transferred donor-derived cytomegalovirus (CMV)
specific cytotoxic T lymphocytes (CTL) as immune reconstitution postallogeneic transplant in …

Comparison of single-dose and escalating-dose regimens of donor lymphocyte infusion for relapse after allografting for chronic myeloid leukemia

F Dazzi, RM Szydlo, C Craddock… - Blood, The Journal …, 2000 - ashpublications.org
Donor lymphocyte infusion (DLI) was originally administered as a single, relatively large
dose of lymphocytes called a bulk dose regimen (BDR). It has since been suggested that the …

Durability of responses following donor lymphocyte infusions for patients who relapse after allogeneic stem cell transplantation for chronic myeloid leukemia

F Dazzi, RM Szydlo, NCP Cross… - Blood, The Journal …, 2000 - ashpublications.org
An analysis was performed of the response to treatment with donor lymphocyte infusions
(DLI) and the survival in 66 consecutive patients who relapsed after primary treatment by …

Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: toxicity, chimerism, and disease responses

KS Peggs, K Thomson, DP Hart, J Geary, EC Morris… - Blood, 2004 - ashpublications.org
Data on the application of donor lymphocyte infusions (DLIs) following reduced-intensity
transplantation (RIT) remain limited. Persistence of host antigen-presenting cells might …

Treatment of relapsed leukemia after unrelated donor marrow transplantation with unrelated donor leukocyte infusions

DL Porter, RH Collins Jr, C Hardy… - Blood, The Journal …, 2000 - ashpublications.org
The efficacy and toxicity of donor leukocyte infusions (DLI) after unrelated donor bone
marrow transplantation (BMT) is largely unknown. We identified 58 recipients of unrelated …

[HTML][HTML] Donor lymphocyte infusion for relapsed hematological malignancies after allogeneic hematopoietic cell transplantation: prognostic relevance of the initial …

M Bar, BM Sandmaier, Y Inamoto, B Bruno… - Biology of Blood and …, 2013 - Elsevier
The impact of donor lymphocyte infusion (DLI) initial cell dose on its outcome is known in
patients with chronic myeloid leukemia but limited in patients with other hematological …

Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning

WA Bethge, U Hegenbart, MJ Stuart, BE Storer… - Blood, 2004 - ashpublications.org
This study retrospectively analyzed data from 446 patients given hematopoietic cell
transplants from HLA-matched related or unrelated donors after conditioning with 2 Gy total …

Donor leukocyte infusions for the treatment of relapsed acute leukemia after allogeneic stem cell transplantation

AW Loren, DL Porter - Bone marrow transplantation, 2008 - nature.com
Allogeneic stem cell transplantation (SCT) offers the only hope for cure for many adults with
acute leukemia. Unfortunately, many patients relapse and die of their disease even after …