Context Invited update on the management of systemic autoimmune Graves disease (GD)
and associated Graves orbitopathy (GO). Evidence acquisition Guidelines, pertinent original …

Adverse drug reactions (ADRs) remain a common and major problem in healthcare. Severe
cutaneous adverse drug reactions (SCARs), such as Stevens–Johnson syndrome …

Graves' disease (GD) is a systemic autoimmune disorder characterized by the infiltration of
thyroid antigen-specific T cells into thyroid-stimulating hormone receptor (TSH-R) …

To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …

Graves' disease is the most frequent cause of hyperthyroidism. Many questions remain
about the choice of diagnostic evaluations and treatment strategy according to clinical …

Most immune-mediated adverse drug reactions (IM-ADRs) involve the skin, and many have
additional systemic features. Severe cutaneous adverse drug reactions (SCARs) are an …

The thionamide antithyroid drugs were discovered in large part following serendipitous
observations by a number of investigators in the 1940s who found that sulfhydryl-containing …

Individuals differ substantially in their response to pharmacological treatment. Personalized
medicine aspires to embrace these inter-individual differences and customize therapy by …

Introduction Graves' disease (GD) is an autoimmune disorder due to loss of tolerance to the
thyrotropin receptor (TSHR) and ultimately caused by stimulatory TSHR antibodies (TSHR …

Adverse drug reactions (ADR) can be broadly categorised as either on‐target or off‐target.
On‐target ADRs arise as a direct consequence of the pharmacological properties of the drug …