Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood

C Anacker, R Hen - Nature Reviews Neuroscience, 2017 - nature.com
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

The effects of aging in the hippocampus and cognitive decline

LEB Bettio, L Rajendran, J Gil-Mohapel - Neuroscience & Biobehavioral …, 2017 - Elsevier
Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …

Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s

P Montay-Gruel, K Petersson, M Jaccard… - Radiotherapy and …, 2017 - Elsevier
This study shows for the first time that normal brain tissue toxicities after WBI can be reduced
with increased dose rate. Spatial memory is preserved after WBI with mean dose rates …

Effects of exercise on anxiety and depression disorders: review of meta-analyses and neurobiological mechanisms

M Wegner, I Helmich, S Machado… - CNS & Neurological …, 2014 - ingentaconnect.com
Anxiety and depression are the most frequently diagnosed psychological diseases showing
a high co-morbidity. They have a severe impact on the lives of the persons concerned. Many …

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

W Deng, JB Aimone, FH Gage - Nature reviews neuroscience, 2010 - nature.com
The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an
important role for adult hippocampal neurogenesis in learning and memory, but its specific …

[HTML][HTML] Zika virus infects neural progenitors in the adult mouse brain and alters proliferation

H Li, L Saucedo-Cuevas, JA Regla-Nava, G Chai… - Cell stem cell, 2016 - cell.com
Zika virus (ZIKV)-related neuropathology is an important global health concern. Several
studies have shown that ZIKV can infect neural stem cells in the developing brain, but …

Exercise builds brain health: key roles of growth factor cascades and inflammation

CW Cotman, NC Berchtold, LA Christie - Trends in neurosciences, 2007 - cell.com
Human and other animal studies demonstrate that exercise targets many aspects of brain
function and has broad effects on overall brain health. The benefits of exercise have been …

Mechanisms and functional implications of adult neurogenesis

C Zhao, W Deng, FH Gage - Cell, 2008 - cell.com
The generation of new neurons is sustained throughout adulthood in the mammalian brain
due to the proliferation and differentiation of adult neural stem cells. In this review, we …

Chemotherapy-induced cognitive impairment (CICI): An overview of etiology and pathogenesis

NM Mounier, AES Abdel-Maged, SA Wahdan, AM Gad… - Life sciences, 2020 - Elsevier
Many cancer patients treated with chemotherapy develop chemotherapy-induced cognitive
impairment (CICI), often referred to as chemo-brain, which manifest during or post-treatment …

Adult hippocampal neurogenesis in depression

A Sahay, R Hen - Nature neuroscience, 2007 - nature.com
The development of new treatments for depression is predicated upon identification of
neural substrates and mechanisms that underlie its etiology and pathophysiology. The …