A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …

Recent updates on phytoconstituent alpha-glucosidase inhibitors: An approach towards the treatment of type two diabetes

H Kashtoh, KH Baek - Plants, 2022 - mdpi.com
Diabetes is a common metabolic disorder marked by unusually high plasma glucose levels,
which can lead to serious consequences such as retinopathy, diabetic neuropathy and …

Natural inhibitors of mammalian α-Amylases as promising drugs for the treatment of metabolic diseases

AP Kalinovskii, OV Sintsova, IN Gladkikh… - International journal of …, 2023 - mdpi.com
α-Amylase is a generally acknowledged molecular target of a distinct class of antidiabetic
drugs named α-glucosidase inhibitors. This class of medications is scarce and rather …

Procyanidins: A promising anti‐diabetic agent with potential benefits on glucose metabolism and diabetes complications

E Qaed, M Almoiliqy, B Al‐Hamyari… - Wound Repair and …, 2023 - Wiley Online Library
Diabetes mellitus (DM) is a complex disease with alarming worldwide health implications
and high mortality rates, largely due to its complications such as cardiovascular disease …

Exploring plant-based alpha-glucosidase inhibitors: promising contenders for combatting type-2 diabetes

S Kumari, R Saini, A Bhatnagar… - Archives of Physiology …, 2023 - Taylor & Francis
Objective: This systematic review aimed to provide comprehensive details on the α-G
inhibitory potential of various bioactive compounds derived from natural sources. Methods: A …

A‐type proanthocyanidins: Sources, structure, bioactivity, processing, nutrition, and potential applications

Y Zeng, L Zhao, K Wang, CMGC Renard… - … Reviews in Food …, 2024 - Wiley Online Library
A‐type proanthocyanidins (PAs) are a subgroup of PAs that differ from B‐type PAs by the
presence of an ether bond between two consecutive constitutive units. This additional C–O …

Free radical scavenging polyphenols isolated from Phyllanthus niruri L. ameliorates hyperglycemia via SIRT1 induction and GLUT4 translocation in in vitro and in vivo …

D Swargiary, B Kashyap, P Sarma, SA Ahmed… - Fitoterapia, 2024 - Elsevier
Type 2 diabetes milletus (T2DM) is a complex multifaceted disorder characterized by insulin
resistance in skeletal muscle. Phyllanthus niruri L. is well reported sub-tropical …

Phytochemical analysis, antioxidant, antimicrobial, and anti-enzymatic properties of Alpinia coriandriodora (sweet ginger) rhizome

X Wu, F Wei, F Ding, N Yang, J Niu, Y Ran… - Frontiers in Plant …, 2023 - frontiersin.org
Alpinia coriandriodora, also known as sweet ginger, is a medicinal and edible plant. A.
coriandriodora rhizome is popularly utilized in traditional Chinese medicine and as …

In Vitro and In Silico Screening Analysis of Artabotrys sumatranus Leaf and Twig Extracts for α-Glucosidase Inhibition Activity and Its Relationship with Antioxidant …

D Rosa, B Elya, M Hanafi, A Khatib, MI Surya - Scientia Pharmaceutica, 2022 - mdpi.com
Artabotrys sumatranus is one of the Artabotrys species, which lives in Sumatera, Java, and
Borneo in Indonesia. No research has been found related to its activity. The objective of this …

Omnifarious fruit polyphenols: an omnipotent strategy to prevent and intervene diabetes and related complication?

Y Chen, X Qie, W Quan, M Zeng, F Qin… - Critical Reviews in …, 2023 - Taylor & Francis
Diabetes mellitus is a metabolic syndrome which cannot be cured. Recently, considerable
interest has been focused on food ingredients to prevent and intervene in complications of …