Adipokines, hepatokines and myokines: focus on their role and molecular mechanisms in adipose tissue inflammation

Y Ren, H Zhao, C Yin, X Lan, L Wu, X Du… - Frontiers in …, 2022 - frontiersin.org
Chronic low-grade inflammation in adipose tissue (AT) is a hallmark of obesity and
contributes to various metabolic disorders, such as type 2 diabetes and cardiovascular …

Klebsiella pneumoniae infection biology: living to counteract host defences

JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

The role of adipokines in chronic inflammation

P Mancuso - ImmunoTargets and therapy, 2016 - Taylor & Francis
Adipose tissue has traditionally been defined as connective tissue that stores excess
calories in the form of triacylglycerol. However, the physiologic functions attributed to …

The role of the adipokine leptin in immune cell function in health and disease

K Kiernan, NJ MacIver - Frontiers in immunology, 2021 - frontiersin.org
Leptin is a critical mediator of the immune response to changes in overall nutrition. Leptin is
produced by adipocytes in proportion to adipose tissue mass and is therefore increased in …

Integrative physiology of pneumonia

LJ Quinton, AJ Walkey, JP Mizgerd - Physiological reviews, 2018 - journals.physiology.org
Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

The role of the immune system in metabolic health and disease

N Zmora, S Bashiardes, M Levy, E Elinav - Cell metabolism, 2017 - cell.com
In addition to the immune system's traditional roles of conferring anti-infectious and anti-
neoplastic protection, it has been recently implicated in the regulation of systemic metabolic …

Adipose tissue, adipokines, and inflammation

G Fantuzzi - Journal of Allergy and clinical immunology, 2005 - Elsevier
White adipose tissue is no longer considered an inert tissue mainly devoted to energy
storage but is emerging as an active participant in regulating physiologic and pathologic …

The impact of obesity on the immune response to infection

JJ Milner, MA Beck - Proceedings of the Nutrition Society, 2012 - cambridge.org
There is strong evidence indicating that excess adiposity negatively impacts immune
function and host defence in obese individuals. This is a review of research findings …

Diabetes and infection: Is there a link?-A mini-review

S Knapp - Gerontology, 2013 - karger.com
Diabetes mellitus is one of the most prevalent conditions in the elderly and is associated
with considerable morbidity and mortality, mainly from cardiovascular and renal …

Adipocytes, innate immunity and obesity: A mini-review

AM Blaszczak, A Jalilvand, WA Hsueh - Frontiers in immunology, 2021 - frontiersin.org
The role of adipose tissue (AT) inflammation in obesity and its multiple related-complications
is a rapidly expanding area of scientific interest. Within the last 30 years, the role of the …