ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human
polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of …

Background Globally, populations are ageing. Typically, physical activity levels decline and
health worsens as we age; however, estimates of the impact of physical inactivity for …

Cognitive abilities are important predictors of educational and occupational performance,
socioeconomic attainment, health, and longevity. Declines in cognitive abilities are linked to …

Objective Physical activity (PA) is associated with a decreased incidence of dementia, but
much of the evidence comes from short follow-ups prone to reverse causation. This meta …

Research into dementia prevention is of paramount importance if the dementia epidemic is
to be halted. Observational studies have identified several potentially modifiable risk factors …

Importance Genetic factors increase risk of dementia, but the extent to which this can be
offset by lifestyle factors is unknown. Objective To investigate whether a healthy lifestyle is …

This article describes the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on …

Since the beginning of time people explored and developed new technologies to make their
activities of daily living less labour intense, more efficient and, consequently, more …

Mental and social health outcomes from a portfolio of women's outdoor tourism products,
with~ 100,000 clients, are analysed using a catalysed netnography of> 1000 social media …

Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …