Mechanisms of SNARE proteins in membrane fusion
R Jahn, DC Cafiso, LK Tamm - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a
family of small conserved eukaryotic proteins that mediate membrane fusion between …
family of small conserved eukaryotic proteins that mediate membrane fusion between …
Mechanics of membrane fusion
LV Chernomordik, MM Kozlov - Nature structural & molecular biology, 2008 - nature.com
Diverse membrane fusion reactions in biology involve close contact between two lipid
bilayers, followed by the local distortion of the individual bilayers and reformation into a …
bilayers, followed by the local distortion of the individual bilayers and reformation into a …
Mechanisms of membrane fusion: disparate players and common principles
S Martens, HT McMahon - Nature reviews Molecular cell biology, 2008 - nature.com
Membrane fusion can occur between cells, between different intracellular compartments,
between intracellular compartments and the plasma membrane and between lipid-bound …
between intracellular compartments and the plasma membrane and between lipid-bound …
How does synaptotagmin trigger neurotransmitter release?
ER Chapman - Annu. Rev. Biochem., 2008 - annualreviews.org
Neurotransmitter release at synapses involves a highly specialized form of membrane fusion
that is triggered by Ca2+ ions and is optimized for speed. These observations were …
that is triggered by Ca2+ ions and is optimized for speed. These observations were …
Helical extension of the neuronal SNARE complex into the membrane
Neurotransmission relies on synaptic vesicles fusing with the membrane of nerve cells to
release their neurotransmitter content into the synaptic cleft, a process requiring the …
release their neurotransmitter content into the synaptic cleft, a process requiring the …
[HTML][HTML] Selective activation of cognate SNAREpins by Sec1/Munc18 proteins
J Shen, DC Tareste, F Paumet, JE Rothman, TJ Melia - Cell, 2007 - cell.com
Summary Sec1/Munc18 (SM) proteins are required for every step of intracellular membrane
fusion, but their molecular mechanism of action has been unclear. In this work, we …
fusion, but their molecular mechanism of action has been unclear. In this work, we …
The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles
Vesicular secretion of neurotransmitter is essential for neuronal communication. Kiss-and-
run is a mode of membrane fusion and retrieval without the full collapse of the vesicle into …
run is a mode of membrane fusion and retrieval without the full collapse of the vesicle into …
Localized, highly efficient secretion of signaling proteins by migrasomes
H Jiao, X Li, Y Li, Y Guo, X Hu, T Sho, Y Luo, J Wang… - Cell research, 2024 - nature.com
Migrasomes, enriched with signaling molecules such as chemokines, cytokines and
angiogenic factors, play a pivotal role in the spatially defined delivery of these molecules …
angiogenic factors, play a pivotal role in the spatially defined delivery of these molecules …
From the stochasticity of molecular processes to the variability of synaptic transmission
C Ribrault, K Sekimoto, A Triller - Nature Reviews Neuroscience, 2011 - nature.com
The variability of the postsynaptic response following a single action potential arises from
two sources: the neurotransmitter release is probabilistic, and the postsynaptic response to …
two sources: the neurotransmitter release is probabilistic, and the postsynaptic response to …
Energetics and dynamics of SNAREpin folding across lipid bilayers
Membrane fusion occurs when SNAREpins fold up between lipid bilayers. How much
energy is generated during SNAREpin folding and how this energy is coupled to the fusion …
energy is generated during SNAREpin folding and how this energy is coupled to the fusion …