[HTML][HTML] Utilizing omics technologies in the investigation of sepsis-induced cardiomyopathy

Z Han, Z Quan, S Zeng, L Wen, H Wang - IJC Heart & Vasculature, 2024 - Elsevier
Sepsis-induced cardiomyopathy (SIC) is a common and high-mortality complication among
critically ill patients. Uncertainties persist regarding the pathogenesis, pathophysiology, and …

Revealing the polarity decrease of cardiomyocyte in the septic cardiomyopathy by a lipid droplets-targeting fluorescent probe with NIR emission

X Zhang, X Li, W Xu, S Li, X Zhou, Z Wang, Q Zhang… - Talanta, 2024 - Elsevier
Septic cardiomyopathy (SCM) is the main cause of death in critically ill patients with sepsis.
However, its definitive pathogenic mechanisms remain to be elucidated. Lipid droplets (LDs) …

Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis

J Li, F Xiao, B Lin, Z Huang, M Wu, H Ma… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction Sepsis-induced cardiomyopathy is a common complication of sepsis and is
associated with higher mortality. To date, effective diagnostic and management strategies …

[HTML][HTML] Comparative Analysis of Hepatic Gene Expression Profiles in Murine and Porcine Sepsis Models

F Halimi, T Vanderhaeghen, S Timmermans… - International Journal of …, 2024 - mdpi.com
Sepsis remains a huge unmet medical need for which no approved drugs, besides
antibiotics, are on the market. Despite the clinical impact of sepsis, its molecular mechanism …

Integration of Mendelian Randomization to Explore the Genetic Influences of Pediatric Sepsis: A Focus on RGL4, ATP9A, MAP3K7CL, and DDX11L2

L Zhang, Q Chu, S Jiang, B Shao - 2024 - researchsquare.com
This study delves into the genetic underpinnings of pediatric sepsis, focusing on the
association and potential mechanisms of action of four key genes: RGL4, ATP9A …

[PDF][PDF] IJC Heart & Vasculature

H Khan, D Gamble, A Mezincescu, H Abbas, A Rudd… - 2021 - researchgate.net
abstract Background: The diagnosis of Takotsubo syndrome is made based on clinical
presentation, ECG, biomarker, imaging and coronary angiography. There is a lack of …