The Drosophila toll pathway in innate immunity: from the core pathway toward effector functions

S Valanne, L Vesala, MK Maasdorp… - The Journal of …, 2022 - journals.aai.org
The fruit fly Drosophila melanogaster Toll signaling pathway has an evolutionarily
conserved role in controlling immune responses. Whereas the microbial recognition …

Pharmacological potential of cyclic nucleotide signaling in immunity

EMQ Ednacot, A Nabhani, DM Dinh… - Pharmacology & …, 2024 - Elsevier
Cyclic nucleotides are important signaling molecules that play many critical physiological
roles including controlling cell fate and development, regulation of metabolic processes, and …

The injection of one recombinant C-type lectin (LvLec) induced the immune response of hemocytes in Litopenaeus vannamei

Y Li, L Pan, J Yu - Fish & Shellfish Immunology, 2022 - Elsevier
To explore the immune function of C-type lectin in shrimp, one recombinant C-type lectin
(LvLec) was injected into Litopenaeus vannamei. There were four treatments in the …

5, 2′-Dibromo-2, 4′, 5′-trihydroxydiphenylmethanone Inhibits LPS-Induced Vascular Inflammation by Targeting the Cav1 Protein

H Yuan, Q Hou, X Feng, Y Zhang, F Yang, R Ge, Q Li - Molecules, 2022 - mdpi.com
Vascular inflammation is directly responsible for atherosclerosis. 5, 2′-Dibromo-2, 4′, 5′-
trihydroxydiphenylmethanone (TDD), a synthetic bromophenol derivative, exhibits anti …

Relaxin affects airway remodeling genes expression through various signal pathways connected with transcription factors

J Wieczfinska, R Pawliczak - International Journal of Molecular Sciences, 2022 - mdpi.com
Fibrosis is one of the parameters of lung tissue remodeling in asthma. Relaxin has emerged
as a natural suppressor of fibrosis, showing efficacy in the prevention of a multiple models of …

[HTML][HTML] Modulation of the NO-cGMP pathway has no effect on olfactory responses in the Drosophila antenna

S Prelic, MN Getahun, S Kaltofen… - Frontiers in Cellular …, 2023 - frontiersin.org
Olfaction is a crucial sensory modality in insects and is underpinned by odor-sensitive
sensory neurons expressing odorant receptors that function in the dendrites as odorant …

Nanomaterial-Driven Precision Immunomodulation: A New Paradigm in Therapeutic Interventions

AAA Aljabali, MA Obeid, O Gammoh, M El-Tanani… - Cancers, 2024 - mdpi.com
Simple Summary This review assesses the integration of nanotechnology and
immunotherapy, with a specific focus on the utilization of nanomaterials to modulate the …

Decoding chikungunya virus non-structural protein 3 interacting partners in THP-1 derived infected macrophages through proteomic profiling

P Srivastava, N Mishra, S Chaudhary, S Sunil - Frontiers in Virology, 2024 - frontiersin.org
Introduction Chikungunya virus (CHIKV), an alphavirus transmitted by mosquitoes, has
instigated several epidemics in recent years, sparking intensive efforts to understand its …