Unveiling a versatile heterocycle: pyrazoline–a review

B Varghese, SN Al-Busafi, FEO Suliman… - RSC advances, 2017 - pubs.rsc.org
The design and synthesis of novel fluorescent heterocyclic dyes is a “hotspot” research area,
due to their favourable photophysical properties and crucial role in charge transfer …

Recent advances in drug discovery against Mycobacterium tuberculosis: Metal-based complexes

CB Scarim, RL de Farias, AV de Godoy Netto… - European Journal of …, 2021 - Elsevier
Metal-based drugs are privileged motifs that act as primary pharmacophores in bioactive
compounds for various diseases, including tuberculosis (TB). This potentially life-threatening …

Design, synthesis, X-ray crystal structures, anticancer, DNA binding, and molecular modelling studies of pyrazole–pyrazoline hybrid derivatives

M Rana, H Hungyo, P Parashar, S Ahmad… - RSC …, 2023 - pubs.rsc.org
We have designed and synthesized three pyrazole analogs (4, 5a, 5b), pyrazole-based
chalcones (6a–6d) and (8a–8h), and N-formyl/acetyl 1, 3, 5-trisubstituted pyrazoline analogs …

Synthesis, single crystal, TD-DFT, molecular dynamics simulation and DNA binding studies of carbothioamide analog

M Rana, S Ahmedi, A Fatima, S Ahmad… - Journal of Molecular …, 2023 - Elsevier
In this work, analog 3b (5-(4-(dimethylamino) phenyl)-3-(4-methoxyphenyl)-4, 5-dihydro-1H-
pyrazole-1-carbothioamide) of pyrazoline derivative was produced based on the active site …

Self-assembly of new cobalt complexes based on [Co (SCN)4], synthesis, empirical, antioxidant activity, and quantum theory investigations

A Ferchichi, J Makhlouf, Y El Bakri, K Saravanan… - Scientific Reports, 2022 - nature.com
The cobalt (II) complexes have been synthesized from the reaction of the cationic entities (3,
4-dimethylaniline (1) and histamine (2)) with metallic salt CoCl2⋅ 6H2O and thiocyanate ion …

Pyrazoline analogs as potential anticancer agents and their apoptosis, molecular docking, MD simulation, DNA binding and antioxidant studies

M Rana, R Arif, FI Khan, V Maurya, R Singh… - Bioorganic …, 2021 - Elsevier
N-formyl pyrazoline derivatives (3a–3l) were designed and synthesized via Michael addition
reaction through cyclization of chalcones with hydrazine hydrate in presence of formic acid …

Design, synthesis and biological evaluation of some new 2-Pyrazoline derivatives as potential anticancer agents

F Tok, Bİ Abas, Ö Çevik, B Koçyiğit-Kaymakçıoğlu - Bioorganic Chemistry, 2020 - Elsevier
A new series of N-(4-(1-Phenyl-5-aryl-4, 5-dihydro-1H-pyrazol-3-yl) phenyl)-4-
substitutedbenzamide derivatives were designed and synthesized from new chalcone …

Physicochemical and Photophysical investigation of newly synthesized carbazole containing pyrazoline-benzothiazole as fluorescent chemosensor for the detection …

AM Asiri, NSM Al-Ghamdi, H Dzudzevic-Cancar… - Journal of Molecular …, 2019 - Elsevier
Abstract Pyrazoline-benzothiazole derivative 3-(2, 5-dimethylthiophen-3-yl)-5-(9-ethyl-9H-
carbazol-3-yl)-4, 5-dihydro-1H-pyrazol-1-yl) benzo [d] thiazole (TCPT) was synthesized by …

Design, DFT and molecular doping studies of metal complexes as a neurotransmitter modulator of autism spectrum disease in preschool children

ZS Al-Garawi, AM Abdallah, RS Sabah… - Journal of Molecular …, 2023 - Elsevier
Coordination of transition metals with pyrazolines has formed complexes of cobalt (II), nickel
(II), copper (II) and zinc (II) utilizing new pyrazoline ligand 3-(2-pyrollyl)-5-(4-bromophenyl)-1 …

Synthesis, structural characterization, antibacterial activity, DFT computational studies and thermal analysis of two new thiocyanate compounds based on 1 …

C Gharbi, B Toumi, S Soudani, F Lefebvre… - Journal of Molecular …, 2022 - Elsevier
Abstract Two hybrid materials,(HPhPip) 2 [Co (NCS) 4](I) and (HPhPip)(NCS)• PhPip (II),
were grown using the slow evaporation method. The characterization of both compounds …