Insertion sequences (ISs), arguably the smallest and most numerous autonomous
transposable elements (TEs), are important players in shaping their host genomes. This …

Integration, excision, and inversion of defined DNA segments commonly occur through site-
specific recombination, a process of DNA breakage and reunion that requires no DNA …

Abstract Prokaryotic Mobile Genetic Elements (MGEs) such as transposons, integrons,
phages and plasmids, play important roles in prokaryotic evolution and in the dispersal of …

Antibiotic resistance in Gram-negative bacteria is often due to the acquisition of resistance
genes from a shared pool. In multiresistant isolates these genes, together with associated …

We have divided this review into two major sections. In one, we have attempted to present
an overview of our current understanding of prokaryotic insertion sequences (IS), their …

DNA as the genetic material is a topic of intense interest in the 21st century, with the
genomes of many organisms having been sequenced. The double helix structure …

Antibiotics have natural functions, mostly involving cell-to-cell signaling networks. The
anthropogenic production of antibiotics, and its release in the microbiosphere results in a …

Enterococci have been recognized as important hospital-acquired pathogens in recent
years, and isolates of E. faecalis and E. faecium are the third-to fourth-most prevalent …

Transposons are ubiquitous in prokaryotic and eukaryotic organisms and are major
determinants of genome structure. Transposition—the movement of discrete segments of …

The ampicillin‐resistance transposon Tn3is the archetype (“Tn3” being synonymous with
“Tn1” or “Tn2”;(1)) of a large and widespread family of transposons with representatives in …