Clostridia: the importance of their exceptional substrate and metabolite diversity for biofuel and biorefinery applications

BP Tracy, SW Jones, AG Fast, DC Indurthi… - Current opinion in …, 2012 - Elsevier
Clostridia are anaerobic Firmicutes producing a large array of metabolites by utilizing simple
and complex carbohydrates, such as cellulose, as well as CO2/H2 or CO. Their exceptional …

Prospective and development of butanol as an advanced biofuel

C Xue, XQ Zhao, CG Liu, LJ Chen, FW Bai - Biotechnology advances, 2013 - Elsevier
Butanol has been acknowledged as an advanced biofuel, but its production through acetone–
butanol–ethanol (ABE) fermentation by clostridia is still not economically competitive, due to …

Stoichiometric and energetic analyses of non-photosynthetic CO2-fixation pathways to support synthetic biology strategies for production of fuels and chemicals

AG Fast, ET Papoutsakis - Current Opinion in Chemical Engineering, 2012 - Elsevier
An increasing focus on environmental sustainability has led to an ongoing global effort to
better understand and engineer platform organisms that economically convert CO 2 and …

One hundred years of clostridial butanol fermentation

HG Moon, YS Jang, C Cho, J Lee… - FEMS microbiology …, 2016 - academic.oup.com
Butanol has been widely used as an important industrial solvent and feedstock for chemical
production. Also, its superior fuel properties compared with ethanol make butanol a good …

Clostridium difficile infection: toxins and non-toxin virulence factors, and their contributions to disease establishment and host response

G Vedantam, A Clark, M Chu, R McQuade… - Gut …, 2012 - Taylor & Francis
Clostridium difficile infection is the leading cause of antibiotic-and healthcare-associated
diarrhea, and its containment and treatment imposes a significant financial burden …

The Clostridium sporulation programs: diversity and preservation of endospore differentiation

MA Al-Hinai, SW Jones… - … and Molecular Biology …, 2015 - Am Soc Microbiol
Bacillus and Clostridium organisms initiate the sporulation process when unfavorable
conditions are detected. The sporulation process is a carefully orchestrated cascade of …

Global Analysis of the Sporulation Pathway of Clostridium difficile

KA Fimlaid, JP Bond, KC Schutz, EE Putnam… - PLoS …, 2013 - journals.plos.org
The Gram-positive, spore-forming pathogen Clostridium difficile is the leading definable
cause of healthcare-associated diarrhea worldwide. C. difficile infections are difficult to treat …

A genetic system for Clostridium ljungdahlii: a chassis for autotrophic production of biocommodities and a model homoacetogen

C Leang, T Ueki, KP Nevin… - Applied and environmental …, 2013 - Am Soc Microbiol
Methods for genetic manipulation of Clostridium ljungdahlii are of interest because of the
potential for production of fuels and other biocommodities from carbon dioxide via microbial …

Biological conversion of methane to liquid fuels: status and opportunities

X Ge, L Yang, JP Sheets, Z Yu, Y Li - Biotechnology advances, 2014 - Elsevier
Methane is the main component of natural gas and biogas. As an abundant energy source,
methane is crucial not only to meet current energy needs but also to achieve a sustainable …

Trash to treasure: production of biofuels and commodity chemicals via syngas fermenting microorganisms

H Latif, AA Zeidan, AT Nielsen, K Zengler - Current Opinion in …, 2014 - Elsevier
Highlights•Syngas fermentation is an attractive prospect for the production of commodity
chemicals.•Syngas fermenting organisms use the Wood–Ljungdahl pathway to metabolize …