Müller glia are the major glial component of the retina. They are one of the last retinal cell
types to be born during development, and they function to maintain retinal homeostasis and …

Unlike mammals, zebrafish are able to regenerate a damaged retina. Key to this
regenerative response are Müller glia that respond to retinal injury by undergoing a …

In humans, various genetic defects or age-related diseases, such as diabetic retinopathies,
glaucoma, and macular degeneration, cause the death of retinal neurons and profound …

Neurodegenerative disorders are significantly increasing in incidence as the age of the
global population continues to climb with improved life expectancy. At present, more than 30 …

Müller glia (MG) dedifferentiation into a cycling population of multipotent progenitors is
crucial to zebrafish retina regeneration. The mechanisms underlying MG dedifferentiation …

Intense light exposure causes photoreceptor apoptosis in dark-adapted adult albino
zebrafish (Danio rerio). Subsequently, Müller glia increase expression of the Achaete-scute …

Unlike mammals, zebrafish can regenerate a damaged retina. This remarkable regenerative
response is mediated by Müller glia (MG) that undergo a reprogramming event that drives …

Retinal dystrophies are a major cause of blindness for which there are currently no curative
treatments. Transplantation of stem cell‐derived neuronal progenitors to replace lost cells …

Müller glia originate from neuroepithelium and are the principal glial cells in the retina.
During retinal development, Müller glia are one of the last cell types to be born. In lower …

Retinal damage in teleosts, unlike mammals, induces robust Müller glia-mediated
regeneration of lost neurons. We examined whether Notch signaling regulates Müller glia …