Ependymal cilia: physiology and role in hydrocephalus

W Ji, Z Tang, Y Chen, C Wang, C Tan, J Liao… - Frontiers in Molecular …, 2022 - frontiersin.org
Cerebrospinal fluid (CSF), a colorless liquid that generally circulates from the lateral
ventricles to the third and fourth ventricles, provides essential nutrients for brain homeostasis …

Molecular classification and therapeutic targets in ependymoma

T Larrew, BF Saway, SR Lowe, A Olar - Cancers, 2021 - mdpi.com
Simple Summary Molecular characterization of ependymoma has revolutionized its
categorization. This new molecular classification has implications particularly in targeted …

Role of the PDZ-scaffold protein NHERF1/EBP50 in cancer biology: from signaling regulation to clinical relevance

J Vaquero, TH Nguyen Ho-Bouldoires, A Claperon… - Oncogene, 2017 - nature.com
The transmission of cellular information requires fine and subtle regulation of proteins that
need to interact in a coordinated and specific way to form efficient signaling networks. The …

Genetic and histologic spatiotemporal evolution of recurrent, multifocal, multicentric and metastatic glioblastoma

MM Georgescu, A Olar - Acta neuropathologica communications, 2020 - Springer
Glioblastoma is the most frequent and aggressive primary brain tumor, characterized by
extensive brain invasion and rarely, systemic metastases. The pathogenesis of metastatic …

Interaction between membranous EBP50 and myosin 9 as a favorable prognostic factor in ovarian clear cell carcinoma

M Nakagawa, T Matsumoto, A Yokoi… - Molecular …, 2023 - Wiley Online Library
Ezrin‐radixin‐moesin‐binding phosphoprotein 50 (EBP50) is a scaffold protein that is
required for epithelial polarity. Knockout (KO) of membranous EBP50 (Me‐EBP50) in …

Immunohistochemical analyses of neural stem cell lineage markers in normal feline brains and glial tumors

K Yoshida, JK Chambers, K Nibe… - Veterinary …, 2024 - journals.sagepub.com
Neural stem cell (NSC) lineage cells have not been fully identified in feline brains, and the
NSC-like nature of feline glial tumors has not been determined. In this study, 6 normal cat …

Differential Tumor Progression Patterns in Skull Base Versus Non–Skull Base Meningiomas: A Critical Analysis from a Long-Term Follow-Up Study and Review of …

AR Savardekar, DP Patra, S Bir, JD Thakur… - World neurosurgery, 2018 - Elsevier
Background To analyze the differences in tumor progression patterns and histopathologic
characteristics between skull base meningiomas (SBMs) and non–skull base meningiomas …

Subependymomas are low-grade heterogeneous glial neoplasms defined by subventricular zone lineage markers

RS D'Amico, M Praver, GJ Zanazzi, ZK Englander… - World Neurosurgery, 2017 - Elsevier
Objective Subependymomas are infrequent, low-grade gliomas associated with the
ventricular system and the spinal cord. Little is known about the origin and natural history of …

[HTML][HTML] NHERF1 between promises and hopes: overview on cancer and prospective openings

M Centonze, C Saponaro, A Mangia - Translational oncology, 2018 - Elsevier
Na+/H+ exchanger regulatory factor 1 (NHERF1) is a scaffold protein, with two tandem PDZ
domains and a carboxyl-terminal ezrin-binding (EB) region. This particular sticky structure is …

Mutation status and epithelial differentiation stratify recurrence risk in chordoid meningioma—a multicenter study with high prognostic relevance

MM Georgescu, A Nanda, Y Li, BC Mobley, PL Faust… - Cancers, 2020 - mdpi.com
Chordoid meningioma is a rare WHO grade II histologic variant. Its molecular alterations or
their impact on patient risk stratification have not been fully explored. We performed a …