The enigmatic endosome–sorting the ins and outs of endocytic trafficking
N Naslavsky, S Caplan - Journal of cell science, 2018 - journals.biologists.com
The early endosome (EE), also known as the sorting endosome (SE) is a crucial station for
the sorting of cargoes, such as receptors and lipids, through the endocytic pathways. The …
the sorting of cargoes, such as receptors and lipids, through the endocytic pathways. The …
Super-resolution microscopy: a closer look at synaptic dysfunction in Alzheimer disease
The synapse has emerged as a critical neuronal structure in the degenerative process of
Alzheimer disease (AD), in which the pathogenic signals of two key players—amyloid-β (Aβ) …
Alzheimer disease (AD), in which the pathogenic signals of two key players—amyloid-β (Aβ) …
SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity
R Martínez-Mármol, R Giordano-Santini, E Kaulich… - Science …, 2023 - science.org
Numerous viruses use specialized surface molecules called fusogens to enter host cells.
Many of these viruses, including the severe acute respiratory syndrome coronavirus 2 …
Many of these viruses, including the severe acute respiratory syndrome coronavirus 2 …
Hericerin derivatives activates a pan‐neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory
R Martínez‐Mármol, YJ Chai, JN Conroy… - Journal of …, 2023 - Wiley Online Library
The traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral
nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here …
nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here …
[HTML][HTML] Tau forms synaptic nano-biomolecular condensates controlling the dynamic clustering of recycling synaptic vesicles
SF Longfield, M Mollazade, TP Wallis… - Nature …, 2023 - nature.com
Neuronal communication relies on the release of neurotransmitters from various populations
of synaptic vesicles. Despite displaying vastly different release probabilities and mobilities …
of synaptic vesicles. Despite displaying vastly different release probabilities and mobilities …
[HTML][HTML] Computerized cell tracking: Current methods, tools and challenges
N Emami, Z Sedaei, R Ferdousi - Visual Informatics, 2021 - Elsevier
In developmental biology, knowledge of cell structure and their (morpho) dynamic behavior,
leads to a comprehensive understanding of their conducts and the mechanisms in which …
leads to a comprehensive understanding of their conducts and the mechanisms in which …
[HTML][HTML] Super-resolved trajectory-derived nanoclustering analysis using spatiotemporal indexing
Single-molecule localization microscopy techniques are emerging as vital tools to unravel
the nanoscale world of living cells by understanding the spatiotemporal organization of …
the nanoscale world of living cells by understanding the spatiotemporal organization of …
[HTML][HTML] Fear extinction is regulated by the activity of long noncoding RNAs at the synapse
Long noncoding RNAs (lncRNAs) represent a multidimensional class of regulatory
molecules that are involved in many aspects of brain function. Emerging evidence indicates …
molecules that are involved in many aspects of brain function. Emerging evidence indicates …
Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1‐SV2 plasma membrane nanocluster for synaptic vesicle entry
The unique nerve terminal targeting of botulinum neurotoxin type A (BoNT/A) is due to its
capacity to bind two receptors on the neuronal plasma membrane: polysialoganglioside …
capacity to bind two receptors on the neuronal plasma membrane: polysialoganglioside …
Cellular uptake of engineered extracellular vesicles: biomechanisms, engineered strategies, and disease treatment
Q Xie, Y Hao, N Li, H Song, X Chen… - Advanced …, 2024 - Wiley Online Library
Abstract Extracellular vesicles (EVs), lipid‐enclosed nanosized membrane vesicles, are
regarded as new vehicles and therapeutic agents in intercellular communication. During …
regarded as new vehicles and therapeutic agents in intercellular communication. During …