Updates in chronic graft‐versus‐host disease management

F Malard, M Mohty - American journal of hematology, 2023 - Wiley Online Library
Chronic graft‐versus‐host disease (cGvHD) remains the most important long‐term
complication of allogeneic hematopoietic cell transplantation (allo‐HCT), but the field has …

B-cell targeting in chronic graft-versus-host disease

R Zeiser, S Sarantopoulos… - Blood, The Journal of the …, 2018 - ashpublications.org
Over the last decade, our understanding of the pathophysiology of chronic graft-versus-host
disease (cGVHD) has improved considerably. In this spotlight, we discuss emerging insights …

[HTML][HTML] IL-21–producing effector Tfh cells promote B cell alloimmunity in lymph nodes and kidney allografts

H Zhang, CB Cavazzoni, MA Podestà, ED Bechu… - JCI insight, 2023 - ncbi.nlm.nih.gov
Follicular helper T (Tfh) cells have been implicated in controlling rejection after allogeneic
kidney transplantation, but the precise subsets, origins, and functions of Tfh cells in this …

B cells in chronic graft-versus-host disease

W McManigle, A Youssef, S Sarantopoulos - Human immunology, 2019 - Elsevier
Allogeneic hematopoietic stem cell transplantation (alloHCT) is the definitive therapy for
numerous otherwise incurable hematologic malignancies and non-malignant diseases. The …

[HTML][HTML] Complex interactions of cellular players in chronic Graft-versus-Host Disease

LM Gail, KJ Schell, P Łacina, J Strobl… - Frontiers in …, 2023 - frontiersin.org
Chronic Graft-versus-Host Disease is a life-threatening inflammatory condition that affects
many patients after allogeneic hematopoietic stem cell transplantation. Although we have …

[HTML][HTML] Management of chronic graft-vs.-host disease in children and adolescents with ALL: present status and model for a personalised management plan

A Sobkowiak-Sobierajska, C Lindemans… - Frontiers in …, 2022 - frontiersin.org
Herein we review current practice regarding the management of chronic graft-vs.-host
disease (cGvHD) in paediatric patients after allogeneic haematopoietic stem cell …

TFH cells in systemic sclerosis

P Beurier, L Ricard, D Eshagh, F Malard… - Journal of Translational …, 2021 - Springer
Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis
with progression to internal organs, vascular impairment and immune dysregulation …

A critical review of belumosudil in adult and pediatric patients with chronic graft-versus-host disease

A Salhotra, K Sandhu, J O'Hearn, H Ali… - Expert Review of …, 2023 - Taylor & Francis
Introduction Chronic graft-versus-host disease (cGVHD) is a complication of allogeneic
hematopoietic cell transplantation (allo-HCT) and is the main cause of late non-relapse …

Adverse events in second- and third-line treatments for acute and chronic graft-versus-host disease: systematic review

VM Velickovic, E McIlwaine, R Zhang… - Therapeutic …, 2020 - journals.sagepub.com
Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is associated
with an increased risk of graft-versus-host disease (GvHD), a strong prognostic predictor of …

Chronic graft-versus-host disease. Part II: Disease activity grading and therapeutic management

E Baumrin, AW Loren, SJ Falk, JW Mays… - Journal of the American …, 2024 - Elsevier
Chronic graft-versus-host disease (cGVHD) is a major complication of allogeneic
hematopoietic cell transplantation and a leading cause of long-term morbidity, nonrelapse …