Microfluidics to mimic blood flow in health and disease

B Sebastian, PS Dittrich - Annual review of fluid mechanics, 2018 - annualreviews.org
Throughout history, capillary systems have aided the establishment of the fundamental laws
of blood flow and its non-Newtonian properties. The advent of microfluidics technology in the …

Microfluidics and microbial engineering

S Kou, D Cheng, F Sun, IM Hsing - Lab on a Chip, 2016 - pubs.rsc.org
The combination of microbial engineering and microfluidics is synergistic in nature. For
example, microfluidics is benefiting from the outcome of microbial engineering and many …

Point-of-care blood coagulation assay based on dynamic monitoring of blood viscosity using droplet microfluidics

L Chen, D Li, X Liu, Y Xie, J Shan, H Huang, X Yu… - ACS …, 2022 - ACS Publications
Monitoring of the coagulation function has applications in many clinical settings. Routine
coagulation assays in the clinic are sample-consuming and slow in turnaround. Microfluidics …

Point-of-care blood coagulation assay enabled by printed circuit board-based digital microfluidics

D Li, X Liu, Y Chai, J Shan, Y Xie, Y Liang, S Huang… - Lab on a Chip, 2022 - pubs.rsc.org
The monitoring of coagulation function has great implications in many clinical settings.
However, existing coagulation assays are simplex, sample-consuming, and slow in …

Rapid, automated, parallel quantitative immunoassays using highly integrated microfluidics and AlphaLISA

Z Tak For Yu, H Guan, M Ki Cheung, WM McHugh… - Scientific reports, 2015 - nature.com
Immunoassays represent one of the most popular analytical methods for detection and
quantification of biomolecules. However, conventional immunoassays such as ELISA and …

Blood cell analysis: from traditional methods to super-resolution microscopy

Z Tian, Y Wei, Y Yu, F Zhou, ZL Huang - Photonics, 2022 - mdpi.com
Blood cell analysis is essential for the diagnosis and identification of hematological
malignancies. The use of digital microscopy systems has been extended in clinical …

On demand release and retrieval of bacteria from microwell arrays using photodegradable hydrogel membranes

AJ Van Der Vlies, N Barua… - ACS Applied Bio …, 2018 - ACS Publications
Microwell arrays are important tools for studying single cell behavior and cell–cell
interactions, both in microbial and mammalian systems. However, retrieval of cells from …

A miniaturized hemoretractometer for blood clot retraction testing

Z Li, X Li, B McCracken, Y Shao, K Ward, J Fu - small, 2016 - Wiley Online Library
Blood coagulation is a critical hemostatic process that must be properly regulated to
maintain a delicate balance between bleeding and clotting. Disorders of blood coagulation …

Deformability measurement of red blood cells using a microfluidic channel array and an air cavity in a driving syringe with high throughput and precise detection of …

YJ Kang, YR Ha, SJ Lee - Analyst, 2016 - pubs.rsc.org
Red blood cell (RBC) deformability has been considered a potential biomarker for
monitoring pathological disorders. High throughput and detection of subpopulations in …

Combining dielectrophoresis and computer vision for precise and fully automated single-cell handling and analysis

N Godino, F Pfisterer, T Gerling, C Guernth-Marschner… - Lab on a Chip, 2019 - pubs.rsc.org
With the advent of single-cell technologies comes the necessity for efficient protocols to
process single cells. We combine dielectrophoresis with open source computer vision …