Methods to accelerate fracture healing–a narrative review from a clinical perspective

B Ganse - Frontiers in Immunology, 2024 - frontiersin.org
Bone regeneration is a complex pathophysiological process determined by molecular,
cellular, and biomechanical factors, including immune cells and growth factors. Fracture …

Delayed Union and Nonunion: Current Concepts, Prevention, and Correction: A Review

KM Bowers, DE Anderson - Bioengineering, 2024 - mdpi.com
Surgical management of fractures has advanced with the incorporation of advanced
technology, surgical techniques, and regenerative therapies, but delayed bone healing …

Reappraisal of clinical trauma trials: the critical impact of anthropometric parameters on fracture gap micro-mechanics—observations from a simulation-based study

M Roland, S Diebels, M Orth, T Pohlemann… - Scientific Reports, 2023 - nature.com
The evidence base of surgical fracture care is extremely sparse with only few sound RCTs
available. It is hypothesized that anthropometric factors relevantly influence mechanical …

Finite element simulations of smart fracture plates capable of cyclic shortening and lengthening: which stroke for which fracture?

M Roland, S Diebels, K Wickert… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction: Bone healing can be improved by axial micromovement, as has been shown in
animals and human patients with external fixators. In the development of smart fracture …

A novel strain-based bone-fracture healing algorithm is able to predict a range of healing outcomes

GT Morgan, L Low, A Ramasamy… - … in Bioengineering and …, 2024 - frontiersin.org
Fracture healing is a complex process which sometimes results in non-unions, leading to
prolonged disability and high morbidity. Traditional methods of optimising fracture …

[HTML][HTML] Case Studies of a Simulation Workflow to Improve Bone Healing Assessment in Impending Non-Unions

TC Maisenbacher, S Libicher, F Erne… - Journal of Clinical …, 2024 - mdpi.com
Background: The healing potential of a fracture is determined by mechanical and biological
factors. Simulation-based workflows can help assess these factors to assist in predicting non …

Experimental and virtual testing of bone-implant systems equipped with the AO Fracture Monitor with regard to interfragmentary movement

K Wickert, M Roland, A Andres, S Diebels… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction: The management of fractured bones is a key domain within orthopedic trauma
surgery, with the prevention of delayed healing and non-unions forming a core challenge …

[HTML][HTML] Finite element analysis of the Fibula's contribution to lower extremity torsional stiffness

A Alito, A Vitali, A Bruschetta, EM Mantineo… - Journal of …, 2025 - Elsevier
Aims The purpose of this article is to investigate the effects of the fibula on the torsional
stiffness of the lower limb. A comprehensive model of the lower limb was constructed …

Influence of implant base material on secondary bone healing: an in silico study

GS Nayak, M Roland, B Wiese, N Hort… - Computer Methods in …, 2024 - Taylor & Francis
The implant material at the fracture site influences fracture healing not only from biological
perspective but also from mechanical perspective. Biodegradable implants such as …

Smart Implants in Orthopädie und Unfallchirurgie

P Orth, M Orth, T Pohlemann - Orthopädie und Unfallchirurgie …, 2024 - thieme-connect.com
Als Diagnoseinstrumente liefern intelligente Implantate Informationen zur Charakterisierung
der Umgebung im Körper, die auf andere Weise nicht gewonnen werden können. Mithilfe …