The construction of carbon− carbon bonds, along with the creation of stereogenic carbon
centers, continues to be an appealing and demanding area of research, and processes in …

The catalysis by primary and secondary amines of electrophilic substitution reactions in the
R-position of carbonyl compounds and related reactions via enamine intermediates is called …

Asymmetric aldol reactions are a powerful method for the construction of carbon–carbon
bonds in an enantioselective fashion. Historically this reaction has been performed in a …

Catalysis with chiral secondary amines (asymmetric aminocatalysis) has become a well‐
established and powerful synthetic tool for the chemo‐and enantioselective functionalization …

The current status of organic synthesis is hampered by costly protecting‐group strategies
and lengthy purification procedures after each synthetic step. To circumvent these problems …

The enantioselective production of compounds is a central theme in current research. The
broad utility of synthetic chiral molecules as single-enantiomer pharmaceuticals, in …

The aldol reaction is one of the most important methods for the stereoselective construction
of polyketide natural products, not only for nature but also for synthetic chemistry. The …

Direct Catalytic Intermolecular α-Allylic Alkylation of Aldehydes by Combination of Transition-Metal
and Organocatalysis Organic Chemistry Portal Abstracts Search: Direct Catalytic Intermolecular …

The use of simple (S)-proline as catalyst for the intermolecular direct aldol reaction at the
beginning of this century became a true milestone in the growth of organocatalysis as a …

l-Proline amides derived from various chiral β-amino alcohols that bear substituents with
various electron natures at their stereogenic centers are prepared and evaluated for …