Neurodegeneration is a complex process that leads to irreversible neuronal damage and
death in spinal cord injury (SCI) and various neurodegenerative diseases, which are …

Leber hereditary optic neuropathy (LHON) is currently estimated as the most frequent
mitochondrial disease (1 in 27,000–45,000). Its molecular pathogenesis and natural history …

The standard scientific method requires that you make an interesting observation, generate
a hypothesis and then design an experiment to test the hypothesis. In ophthalmology, as in …

Purpose.: To report the serial evaluation of asymptomatic eyes of subjects with mutated
G11778A mitochondrial DNA. Methods.: Forty-five asymptomatic G11778A Leber hereditary …

Introduction Burning mouth syndrome is a painful condition of the oral cavity with ambiguous
pathogenesis and diagnosis. Neuron-specific enolase is increased in several conditions …

The peculiar biology of mitochondrial DNA (mtDNA) potentially has detrimental
consequences for organismal health and lifespan. Typically, eukaryotic cells contain …

Purpose: The photopic negative response (PhNR) is an electrophysiological method that
provides retinal ganglion cell function assessment using full-field stimulation that does not …

Aim Neuron‐specific enolase as a potential biomarker of diabetic retinopathy, a
neurovascular disease, had not been fully explored. We aimed to investigate the …

Objective Subclinical abnormalities, including microangiopathy, swelling of nerve fibers,
visual field abnormalities and visual functional impairments had been reported in Leber's …

Background We aimed to evaluate serum levels of S-100 beta (S-100β) and neuron specific
enolase (NSE) in patients with coronary heart disease (CHD) after off-pump versus on-pump …