Comparative whole-genome resequencing to uncover selection signatures linked to litter size in Hu Sheep and five other breeds

T Zhong, D Hou, Q Zhao, S Zhan, L Wang, L Li… - BMC genomics, 2024 - Springer
Hu sheep (HS), a breed of sheep carrying the FecB mutation gene, is known for its “year-
round estrus and multiple births” and is an ideal model for studying the high fecundity …

DNA Hypomethylation–Mediated Transcription Dysregulation Participates in Pathogenesis of Polycystic Ovary Syndrome

P Cao, H Li, P Wang, X Zhang, Y Guo, K Zhao… - The American Journal of …, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly heterogeneous and genetically complex
endocrine disorder. Although the etiology remains mostly elusive, growing evidence …

Evaluating the role of DNA methyltransferases in trophoblast fusion and preeclampsia development: Insights from methylation‐regulated genes

YF Yang, ZH Li, TH Liu, C Li, YL Xie, LX Ge… - The FASEB …, 2024 - Wiley Online Library
The etiology of preeclampsia (PE), a complex and multifactorial condition, remains
incompletely understood. DNA methylation, which is primarily regulated by three DNA …

Bioinformatic network analysis on the molecular interactions between Parkinson's disease, alpha-synuclein, and infertility condition

V Krishnan, SS Patel, P Shenoy, J Cottrell - Middle East Fertility Society …, 2023 - Springer
Background Parkinson's disease (PD) is a neurodegenerative condition that is characterized
by a progressive decline of neural pathways, and its pathology is associated with alpha …

TNFAIP3 derived from skeletal stem cells alleviated rat osteoarthritis by inhibiting the necroptosis of subchondral osteoblasts

XT Li, ZL Li, PL Li, FY Wang, XY Zhang, YX Wang… - Stem Cells, 2024 - academic.oup.com
Recent investigations have shown that the necroptosis of tissue cells in joints is important in
the development of osteoarthritis (OA). This study aimed to investigate the potential effects of …