[HTML][HTML] Solid lipid nanoparticles: An effective lipid-based technology for cancer treatment

M Akanda, MDSH Mithu, D Douroumis - Journal of Drug Delivery Science …, 2023 - Elsevier
Solid lipid nanoparticles (SLN) are considered at the forefront of nanotechnology's rapidly
developing field, with several potential applications in drug delivery and research. SLN …

Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges

T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Biochemical properties and anti-biofilm activity of chitosan-immobilized papain

DR Baidamshina, VA Koroleva, SS Olshannikova… - Marine Drugs, 2021 - mdpi.com
Chitosan, the product of chitin deacetylation, is an excellent candidate for enzyme
immobilization purposes. Here we demonstrate that papain, an endolytic cysteine protease …

Colorectal cancer stem cells: A review of targeted drug delivery by gold nanoparticles

MH Mohd-Zahid, R Mohamud, CAC Abdullah, JK Lim… - RSC Advances, 2020 - pubs.rsc.org
Colorectal cancer (CRC) is one of the most common cancers with equal probability of
affecting both men and women worldwide. Recently, the newly emerged theory of cancer …

Myricetin loaded in solid lipid nanoparticles induces apoptosis in the HT-29 colorectal cancer cells via mitochondrial dysfunction

H Alidadi, A Ashtari, A Samimi, MA Karami… - Molecular Biology …, 2022 - Springer
Abstract Background Among the flavonoids, Myricetin (MCN) has negligible side effects and
anti-cancer properties. However, the therapeutic potential of MCN has been limited mainly …

Inclusion Complexes Between β‐cyclodextrin and the Anticancer Drug 5‐Fluorouracil for its Solubilization: a Molecular Dynamics Study at Different Stoichiometries

G Raffaini, S Elli, F Ganazzoli… - Macromolecular …, 2022 - Wiley Online Library
Cyclodextrins (CDs) are natural macrocyclic oligosaccharides able to solubilize hydrophobic
drugs in water improving their bioavailability, thanks to favorable noncovalent interactions …

Preparation and characterization of acetylated starch/papain composites

S Boonkerd, H Hao, L Wantha - RSC advances, 2024 - pubs.rsc.org
This research aimed to prepare and characterize acetylated starch/papain composites by
encapsulating papain within acetylated cassava starch with a low degree of substitution …

Formulation of Morus alba extract loaded Solid Lipid Nanoparticles: In Silico, Characterizations, and In vitro cytotoxicity study

NN Palei, M Sabapati, S Samajdar… - Drug Development and …, 2024 - Taylor & Francis
Objective This study aimed to formulate Morus alba leaf extract (MAE) loaded solid lipid
nanoparticles (SLNs) and investigate its cytotoxic potential using MDA-MB231 cell line …

Breaking the barrier of cancer through papaya extract and their formulation

S Saha, TK Giri - Anti-Cancer Agents in Medicinal Chemistry …, 2019 - ingentaconnect.com
Background: In the last decade, many new avenues of cancer treatment have opened up but
the costs of treatment have sky-rocketed too. Hence, screening of indigenously available …

Solid Lipid Nanoparticles for Delivery of 5-Fluorouracil and Andrographolide: A Combination Approach for the Treatment of Cancer

Z Malik, R Parveen, P Basist, SA Husain, S Ahmad - BioNanoScience, 2024 - Springer
The objective of this study was to develop a nanoformulation of 5-fluorouracil (5-FU)
combined with Andrographolide (AG) to synergize their anticancer activity, reduce the dose …