Background Folate-sensitive neural tube defects (NTDs) are an important, preventable
cause of morbidity and mortality worldwide. There is a need to describe the current global …

Background Hydrocephalus is a debilitating disorder, affecting all age groups. Evaluation of
its global epidemiology is required for healthcare planning and resource allocation …

Objective To investigate the prevalence of congenital heart disease (CHD) in China based
on a large prospective multicenter screening study. Study design A total of 122 765 …

Introduction Several studies have reported on the maternal age‐associated risks of
congenital anomalies. However, there is a paucity of studies with comprehensive review of …

Background Anencephaly is a fatal congenital anomaly characterized by the absence of
brain hemispheres and cranial arch. Timely preventive measures can be taken by knowing …

Background During the first three months of pregnancy, the developing embryo may be
susceptible to external and internal factors, which may lead to structural and functional …

Background Congenital malformation (CM) is a leading cause of infant mortality. We
hypothesized that the current estimates of the prevalence of CM are obsolete because of the …

Background Birth defects are defined as structural and functional defects that develop during
the organogenesis period and present at birth or detected later in life. They are one of the …

Congenital anomalies (CAs) are a leading cause of morbidity and mortality in early life. We
aimed to assess the incidence, risk factors, and outcomes of major CAs in the State of Qatar …

Background The early stage of embryo development is extremely vulnerable to various
teratogenic factors, leading to congenital anomalies. In Ethiopia, a significant number of …