Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
Blood GFAP as an emerging biomarker in brain and spinal cord disorders
Blood-derived biomarkers for brain and spinal cord diseases are urgently needed. The
introduction of highly sensitive immunoassays led to a rapid increase in the number of …
introduction of highly sensitive immunoassays led to a rapid increase in the number of …
Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US …
Background The prognostic value of glial fibrillary acidic protein (GFAP) and ubiquitin C-
terminal hydrolase L1 (UCH-L1) as day-of-injury predictors of functional outcome after …
terminal hydrolase L1 (UCH-L1) as day-of-injury predictors of functional outcome after …
Blood biomarkers for mild traumatic brain injury: a selective review of unresolved issues
Background The use of blood biomarkers after mild traumatic brain injury (mTBI) has been
widely studied. We have identified eight unresolved issues related to the use of five …
widely studied. We have identified eight unresolved issues related to the use of five …
[HTML][HTML] Blood-based biomarkers of inflammation in mild traumatic brain injury: A systematic review
K Visser, M Koggel, J Blaauw, HJ van der Horn… - Neuroscience & …, 2022 - Elsevier
Abstract VISSER, K., M. Koggel, J. Blaauw, HJvd Horn, B. Jacobs, and Jvd Naalt. Blood
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …
Considering biological sex in traumatic brain injury
A Biegon - Frontiers in neurology, 2021 - frontiersin.org
Published epidemiological studies of traumatic brain injury (TBI) of all severities consistently
report higher incidence in men. Recent increases in the participation of women in sports and …
report higher incidence in men. Recent increases in the participation of women in sports and …
Incremental prognostic value of acute serum biomarkers for functional outcome after traumatic brain injury (CENTER-TBI): an observational cohort study
Background Several studies have reported an association between serum biomarker values
and functional outcome following traumatic brain injury. We aimed to examine the …
and functional outcome following traumatic brain injury. We aimed to examine the …
Unique diagnostic signatures of concussion in the saliva of male athletes: the Study of Concussion in Rugby Union through MicroRNAs (SCRUM)
V Di Pietro, P O'Halloran, CN Watson… - British journal of sports …, 2021 - bjsm.bmj.com
Objective To investigate the role of salivary small non-coding RNAs (sncRNAs) in the
diagnosis of sport-related concussion. Methods Saliva was obtained from male professional …
diagnosis of sport-related concussion. Methods Saliva was obtained from male professional …
S100B, GFAP, UCH-L1 and NSE as predictors of abnormalities on CT imaging following mild traumatic brain injury: a systematic review and meta-analysis of …
Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …
A framework to advance biomarker development in the diagnosis, outcome prediction, and treatment of traumatic brain injury
EA Wilde, IB Wanner, K Kenney, J Gill… - Journal of …, 2022 - liebertpub.com
Multi-modal biomarkers (eg, imaging, blood-based, physiological) of unique traumatic brain
injury (TBI) endophenotypes are necessary to guide the development of personalized and …
injury (TBI) endophenotypes are necessary to guide the development of personalized and …