Cellular, molecular, and clinical mechanisms of action of deep brain stimulation—a systematic review on established indications and outlook on future developments
Deep brain stimulation (DBS) has been successfully used to treat movement disorders, such
as Parkinson's disease, for more than 25 years and heralded the advent of electrical …
as Parkinson's disease, for more than 25 years and heralded the advent of electrical …
Biomarkers and stimulation algorithms for adaptive brain stimulation
The goal of this review is to describe in what ways feedback or adaptive stimulation may be
delivered and adjusted based on relevant biomarkers. Specific treatment mechanisms …
delivered and adjusted based on relevant biomarkers. Specific treatment mechanisms …
Electrodeposited platinum-iridium coating improves in vivo recording performance of chronically implanted microelectrode arrays
Reliable single unit neuron recordings from chronically implanted microelectrode arrays
(MEAs) are essential tools in the field of neural engineering. However, following …
(MEAs) are essential tools in the field of neural engineering. However, following …
The therapeutic potential of non-invasive and invasive cerebellar stimulation techniques in hereditary ataxias
The degenerative ataxias comprise a heterogeneous group of inherited and acquired
disorders that are characterized by a progressive cerebellar syndrome, frequently in …
disorders that are characterized by a progressive cerebellar syndrome, frequently in …
Pallidal deep brain stimulation modulates excessive cortical high β phase amplitude coupling in Parkinson disease
M Malekmohammadi, N AuYong, J Ricks-Oddie… - Brain stimulation, 2018 - Elsevier
Objective Deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus
pallidus internus (GPi) are equally efficacious in the management of Parkinson disease …
pallidus internus (GPi) are equally efficacious in the management of Parkinson disease …
Simulation of closed-loop deep brain stimulation control schemes for suppression of pathological beta oscillations in Parkinson's disease
JE Fleming, E Dunn, MM Lowery - Frontiers in neuroscience, 2020 - frontiersin.org
This study presents a computational model of closed-loop control of deep brain stimulation
(DBS) for Parkinson's disease (PD) to investigate clinically viable control schemes for …
(DBS) for Parkinson's disease (PD) to investigate clinically viable control schemes for …
A review of neurophysiological effects and efficiency of waveform parameters in deep brain stimulation
Neurostimulation has diverse clinical applications and potential as a treatment for medically
refractory movement disorders, epilepsy, and other neurological disorders. However, the …
refractory movement disorders, epilepsy, and other neurological disorders. However, the …
Cortical network effects of subthalamic deep brain stimulation in a thalamo-cortical microcircuit model
AA Farokhniaee, MM Lowery - Journal of Neural Engineering, 2021 - iopscience.iop.org
Objective. High frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN)
suppresses excessive beta band (∼ 13–30 Hz) activity of the motor cortex in Parkinson's …
suppresses excessive beta band (∼ 13–30 Hz) activity of the motor cortex in Parkinson's …
Efficient suppression of parkinsonian beta oscillations in a closed-loop model of deep brain stimulation with amplitude modulation
F Bahadori-Jahromi, S Salehi, M Madadi Asl… - Frontiers in human …, 2023 - frontiersin.org
Introduction Parkinson's disease (PD) is a movement disorder characterized by the
pathological beta band (15–30 Hz) neural oscillations within the basal ganglia (BG). It is …
pathological beta band (15–30 Hz) neural oscillations within the basal ganglia (BG). It is …
Excitatory deep brain stimulation quenches beta oscillations arising in a computational model of the subthalamo-pallidal loop
Parkinson's disease (PD) is associated with abnormal β band oscillations (13–30 Hz) in the
cortico-basal ganglia circuits. Abnormally increased striato-pallidal inhibition and …
cortico-basal ganglia circuits. Abnormally increased striato-pallidal inhibition and …