Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal
and fetal morbidity and mortality. The disease presents with new-onset hypertension and …

Preeclampsia (PE) is a serious pregnancy complication, affecting about 5–7% of
pregnancies worldwide and is characterized by hypertension and damage to multiple …

Background Preeclampsia complicates approximately 3–5% of pregnancies and remains a
major cause of maternal and neonatal morbidity and mortality. It shares pathogenic …

Preeclampsia is a pregnancy-specific disease characterized by new onset hypertension and
proteinuria after 20 wk of gestation. It is a leading cause of maternal and fetal morbidity and …

Preeclampsia is a pregnancy-associated disorder characterized by hypertension, and could
lead to maternal and fetal morbidity and mortality; however, the pathophysiological …

Objectives: To improve preclinical drug testing during pregnancy, we developed multiple
microfluidic organ-on-chip (OOC) devices that represent the structure, functions, and …

Preeclampsia is a common hypertensive disorder of pregnancy associated with
considerable neonatal and maternal morbidities and mortalities. However, the exact cause …

Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …

An imbalance in the angiogenesis axis during pregnancy manifests as clinical preeclampsia
because of endothelial dysfunction. Circulating soluble fms-like tyrosine kinase 1 (sFLT-1) …

Abstract Purpose of Review To review the rationale and biological plausibility and discuss
the current research on novel interventions for the prevention of preeclampsia. Recent …