Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …

Interleukin (IL)-6 is a pleotropic cytokine with various physiological and pathophysiological
functions in different cells and tissues. In cells residing within white adipose tissue, several …

We investigated the relationship between gut health, visceral fat dysfunction and metabolic
disorders in diet-induced obesity. C57BL/6J mice were fed control or high saturated fat diet …

Obesity is currently the most important contributor to ill health and expenditure worldwide.
More alarming is the fact that the pediatric population parallels adults, with obesity closely …

Obesity is associated with altered gut microbiota composition and impaired gut barrier
function. These changes, together with interrelated mesenteric adipose tissue inflammation …

Adipose tissues are not homogeneous and show site-specific properties. An elusive and
understudied adipose tissue depot, most likely due to its limited accessibility, is the …

Cholesterol plays essential structural and signaling roles in mammalian cells, but too much
cholesterol can cause cytotoxicity. Acyl-CoA: cholesterol acyltransferases 1 and 2 (ACAT1/2) …

Aims. The study aims to determine the effect of long-chain saturated and polyunsaturated
(PUFA) fatty acids, specifically palmitic acid (PA; 16: 0), docosahexaenoic acid (DHA; 22: 6n …

Myostatin negatively regulates skeletal muscle growth and appears upregulated in human
obesity and associated with insulin resistance. However, observations are confounded by …

Endocannabinoids (ECs) mediate effects via cannabinoid receptor types 1 and 2 (CB1 and
2) and transient receptor potential channel-vanilloid subfamily member 1 (TRPV1) channels …