Ion mobility mass spectrometry (IM-MS) for structural biology: insights gained by measuring mass, charge, and collision cross section

E Christofi, P Barran - Chemical Reviews, 2023 - ACS Publications
The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …

Ultra-high-performance liquid chromatography high-resolution mass spectrometry variants for metabolomics research

L Perez de Souza, S Alseekh, F Scossa, AR Fernie - Nature Methods, 2021 - nature.com
Ultra-high-performance liquid chromatography high-resolution mass spectrometry (UHPLC–
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …

Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

[HTML][HTML] Software tools and approaches for compound identification of LC-MS/MS data in metabolomics

I Blaženović, T Kind, J Ji, O Fiehn - Metabolites, 2018 - mdpi.com
The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …

Recommendations for reporting ion mobility Mass Spectrometry measurements

V Gabelica, AA Shvartsburg, C Afonso… - Mass spectrometry …, 2019 - Wiley Online Library
Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics

G Paglia, AJ Smith, G Astarita - Mass Spectrometry Reviews, 2022 - Wiley Online Library
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

Native mass spectrometry: recent progress and remaining challenges

KR Karch, DT Snyder, SR Harvey… - Annual review of …, 2022 - annualreviews.org
Native mass spectrometry (nMS) has emerged as an important tool in studying the structure
and function of macromolecules and their complexes in the gas phase. In this review, we …

[HTML][HTML] On-site detection of volatile organic compounds (VOCs)

R Epping, M Koch - Molecules, 2023 - mdpi.com
Volatile organic compounds (VOCs) are of interest in many different fields. Among them are
food and fragrance analysis, environmental and atmospheric research, industrial …

[HTML][HTML] Collision cross section compendium to annotate and predict multi-omic compound identities

JA Picache, BS Rose, A Balinski, KL Leaptrot… - Chemical …, 2019 - pubs.rsc.org
Ion mobility mass spectrometry (IM-MS) expands the analyte coverage of existing multi-omic
workflows by providing an additional separation dimension as well as a parameter for …

Cryo-EM of soft-landed β-galactosidase: Gas-phase and native structures are remarkably similar

TK Esser, J Böhning, A Önür, DK Chinthapalli… - Science …, 2024 - science.org
Native mass spectrometry (MS) has become widely accepted in structural biology, providing
information on stoichiometry, interactions, homogeneity, and shape of protein complexes …