High-grade gliomas are rapidly progressing tumors of the central nervous system (CNS) with
a very poor prognosis despite extensive resection combined with radiation and/or …

Abstract Salvia miltiorrhiza Bunge (Danshen in Chinese) is a classical Huoxue Huayu (a
traditional Chinese medical term means promoting blood circulation and removing blood …

Serotonin (5-hydroxytryptamine, 5-HT) is a biogenic monoamine that acts as a
neurotransmitter in the central nervous system, local mediator in the gut and vasoactive …

Despite considerable amount of research, the poor prognosis of patients diagnosed with
glioblastoma multiforme (GBM) critically needs new drug development to improve clinical …

Background In recent years, the significance of the nervous system in the tumor
microenvironment has gained increasing attention. The bidirectional communication …

High-grade gliomas are the most common primary brain tumors. Their malignancy is
promoted by the complex crosstalk between different cell types in the central nervous …

Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally
and cause distant metastasis. Chondrosarcoma shows a predilection for metastasis to the …

Glioblastoma (GBM) is characterized by extremely poor prognoses, despite the use of gross
surgical resection, alkylating chemotherapeutic agents, and radiotherapy. Evidence …

Background Osteosarcoma is the most common primary malignant tumor in children and
young adults, and its treatment requires effective therapeutic approaches because of a high …

Curcumin, a polyphenolic compound isolated from Curcuma longa (Turmeric) is widely used
in traditional Ayurvedic medicine. Its potential therapeutic effects on a variety of diseases …