A review of potential novel glaucoma therapeutic options independent of intraocular pressure

WS Shalaby, OM Ahmed, M Waisbourd, LJ Katz - Survey of Ophthalmology, 2022 - Elsevier
Glaucoma, a progressive optic neuropathy characterized by retinal ganglion cell
degeneration and visual field loss, is the leading cause of irreversible blindness worldwide …

Protection of retinal ganglion cells in glaucoma: Current status and future

J Shen, Y Wang, K Yao - Experimental Eye Research, 2021 - Elsevier
Glaucoma is a neuropathic disease that causes optic nerve damage, loss of retinal ganglion
cells (RGCs), and visual field defects. Most glaucoma patients have no early signs or …

Vision modulation, plasticity and restoration using non-invasive brain stimulation–An IFCN-sponsored review

BA Sabel, G Thut, J Haueisen, P Henrich-Noack… - Clinical …, 2020 - Elsevier
The visual system has one of the most complex structures of all sensory systems and is
perhaps the most important sense for everyday life. Its functional organization was …

[HTML][HTML] Implications of neural plasticity in retinal prosthesis

D Caravaca-Rodriguez, SP Gaytan… - … & visual science, 2022 - tvst.arvojournals.org
Retinal degenerative diseases such as retinitis pigmentosa cause a progressive loss of
photoreceptors that eventually prevents the affected person from perceiving visual …

Electrical, electromagnetic, ultrasound wave therapies, and electronic implants for neuronal rejuvenation, neuroprotection, axonal regeneration, and IOP reduction

NA Sharif - Journal of Ocular Pharmacology and Therapeutics, 2023 - liebertpub.com
The peripheral nervous system (PNS) of mammals and nervous systems of lower organisms
possess significant regenerative potential. In contrast, although neural plasticity can provide …

Electrical stimulation induces retinal Müller cell proliferation and their progenitor cell potential

S Enayati, K Chang, H Achour, KS Cho, F Xu, S Guo… - Cells, 2020 - mdpi.com
Non-invasive electrical stimulation (ES) is increasingly applied to improve vision in
untreatable eye conditions, such as retinitis pigmentosa and age-related macular …

Direct modulation of microglial function by electrical field

A Lennikov, M Yang, K Chang, L Pan… - Frontiers in Cell and …, 2022 - frontiersin.org
Non-invasive electric stimulation (ES) employing a low-intensity electric current presents a
potential therapeutic modality that can be applied for treating retinal and brain …

An in-silico analysis of retinal electric field distribution induced by different electrode design of trans-corneal electrical stimulation

Z Lu, M Zhou, T Guo, J Liang, W Wu… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. Trans-corneal electrical stimulation (TcES) produces therapeutic effects on many
ophthalmic diseases non-invasively. Existing clinical TcES devices use largely variable …

Therapeutic strategies for attenuation of retinal ganglion cell injury in optic neuropathies: concepts in translational research and therapeutic implications

L Fu, SS Kwok, YK Chan, JS Ming Lai… - BioMed research …, 2019 - Wiley Online Library
Retinal ganglion cell (RGC) death is the central and irreversible endpoint of optic
neuropathies. Current management of optic neuropathies and glaucoma focuses on …

Noninvasive electrical stimulation improves photoreceptor survival and retinal function in mice with inherited photoreceptor degeneration

H Yu, S Enayati, K Chang, K Cho… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: Neurons carry electrical signals and communicate via electrical activities. The
therapeutic potential of electrical stimulation (ES) for the nervous system, including the …