Abstract Iron-sulfur (Fe–S) clusters are essential cofactors most commonly known for their
role mediating electron transfer within the mitochondrial respiratory chain. The Fe–S cluster …

Mitochondria are intracellular organelles involved in energy production, cell metabolism and
cell signaling. They are essential not only in the process of ATP synthesis, lipid metabolism …

Succinate dehydrogenase inhibitors (SDHIs) have become one of the fastest growing
classes of new fungicides since entering the market, and have attracted increasing attention …

In recent years, widespread outbreak of numerous infectious diseases across the globe has
created havoc among the population. Particularly, the inhabitants of tropical and sub-tropical …

The respiratory electron transport chain (ETC) couples electron transfer from organic
substrates onto molecular oxygen with proton translocation across the inner mitochondrial …

Reactive oxygen species (ROS) are unstable reactive molecules that are toxic to cells.
Regulation of ROS homeostasis is crucial to protect cells from dysfunction, senescence, and …

Abstract Mitochondrial Oxidative Phosphorylation (OXPHOS) provides ATP for driving
cellular functions. In plants, OXPHOS takes place in the context of photosynthesis. Indeed …

Succinate dehydrogenase (SDH) also known as complex II or succinate: quinone
oxidoreductase is an enzyme involved in both oxidative phosphorylation and tricarboxylic …

Abstract Significance: Reduction-oxidation (Redox) status operates as a major integrator of
subcellular and extracellular metabolism and is simultaneously itself regulated by metabolic …

Though succinate accumulation is associated with reactive oxygen species (ROS)
production and neuronal injury, which play critical roles in epilepsy, it is unclear whether …