Biomaterialomics: Data science-driven pathways to develop fourth-generation biomaterials
Conventional approaches to developing biomaterials and implants require intuitive tailoring
of manufacturing protocols and biocompatibility assessment. This leads to longer …
of manufacturing protocols and biocompatibility assessment. This leads to longer …
Advancing bone tissue engineering one layer at a time: a layer-by-layer assembly approach to 3D bone scaffold materials
The layer-by-layer (LbL) assembly technique has shown excellent potential in tissue
engineering applications. The technique is mainly based on electrostatic attraction and …
engineering applications. The technique is mainly based on electrostatic attraction and …
Biomimetic extracellular environment based on natural origin polyelectrolyte multilayers
Surface modification of biomaterials is a well‐known approach to enable an adequate
biointerface between the implant and the surrounding tissue, dictating the initial acceptance …
biointerface between the implant and the surrounding tissue, dictating the initial acceptance …
Primary human osteoblasts cultured in a 3D microenvironment create a unique representative model of their differentiation into osteocytes
Microengineered systems provide an in vitro strategy to explore the variability of individual
patient response to tissue engineering products, since they prefer the use of primary cell …
patient response to tissue engineering products, since they prefer the use of primary cell …
High-throughput screening approaches and combinatorial development of biomaterials using microfluidics
D Barata, C van Blitterswijk, P Habibovic - Acta biomaterialia, 2016 - Elsevier
From the first microfluidic devices used for analysis of single metabolic by-products to highly
complex multicompartmental co-culture organ-on-chip platforms, efforts of many …
complex multicompartmental co-culture organ-on-chip platforms, efforts of many …
Multifunctional biomaterials: combining material modification strategies for engineering of cell-contacting surfaces
AS Mertgen, VT Trossmann, AG Guex… - … applied materials & …, 2020 - ACS Publications
In the human body, cells in a tissue are exposed to signals derived from their specific
extracellular matrix (ECM), such as architectural structure, mechanical properties, and …
extracellular matrix (ECM), such as architectural structure, mechanical properties, and …
Layer-by-layer assembly as a robust method to construct extracellular matrix mimic surfaces to modulate cell behavior
Cellular behavior is crucially dependent on the biophysical and biochemical properties of
the extracellular matrix (ECM), in which the properties of biochemistry, topography, and …
the extracellular matrix (ECM), in which the properties of biochemistry, topography, and …
[HTML][HTML] Substrate stiffness differentially impacts autophagy of endothelial cells and smooth muscle cells
Stiffening of blood vessels is one of the most important characteristics in the process of many
cardiovascular pathologies such as atherosclerosis, angiosteosis, and vascular aging …
cardiovascular pathologies such as atherosclerosis, angiosteosis, and vascular aging …
Co-immobilization of CD133 antibodies, vascular endothelial growth factors, and REDV peptide promotes capture, proliferation, and differentiation of endothelial …
Y Duan, S Yu, P Xu, X Wang, X Feng, Z Mao, C Gao - Acta biomaterialia, 2019 - Elsevier
Capture of endothelial progenitor cells (EPCs) in situ has been considered as a promising
strategy for the rapid endothelialization and long-term patency of artificial blood vessels and …
strategy for the rapid endothelialization and long-term patency of artificial blood vessels and …