A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

Various factors could damage the structure and integrity of skin to cause wounds.
Nonhealing or chronic wounds seriously affect the well-being of patients and bring heavy …

Over the past millennia, life expectancy has drastically increased. While a mere 25 years
during Bronze and Iron ages, life expectancy in many European countries and in Japan is …

Aging is a gradual, continuous series of natural changes in biological, physiological,
immunological, environmental, psychological, behavioral, and social processes. Aging …

Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

Chronic kidney disease (CKD) causes considerable morbidity, mortality, and health
expenditures worldwide. Obesity is a significant risk factor for CKD development, partially …

Knee osteoarthritis (KOA) is a common chronic disease in orthopedics, which brings great
pain to patients' life and spirit. Therefore, it is necessary to elucidate the pathogenesis of …

The geroscience hypothesis proposes that addressing the biology of aging could directly
prevent the onset or mitigate the severity of multiple chronic diseases. Understanding the …

The kidney is a metabolically active organ that requires energy to drive processes such as
tubular reabsorption and secretion, and shows a decline in function with advancing age …