Alpha-Lipoic acid (ALA) is a natural antioxidant synthetized by plants and animals, identified
as a catalytic agent for oxidative decarboxylation of pyruvate and α-ketoglutarate. In this …

Objective Infertility is an increasingly frequent health condition, which may depend on
female or male factors. Oxidative stress (OS), resulting from a disrupted balance between …

Abstract Ethnopharmacological relevance Zuogui Pill (ZGP) is a traditional herbal formula of
Chinese Medicine with a long history of use in alleviating ovarian aging. Aim of the study To …

Oocyte quality is closely related to female fertility. Nevertheless, core nutritional metabolites
influencing oocyte quality are unclear. Herein, comprehensive metabolomics analysis of …

The aim of this review is to summarize our current understanding of the molecular
mechanism for the glucose metabolism, especially pyruvate dehydrogenase (PDH), during …

Purpose In contrast to most other mammals, canine oocytes are ovulated in an immature
state and undergo oocyte maturation within the oviduct during the estrus stage. The aim of …

Oxidative stress inevitably occurs during oocyte maturation in vitro. α‐lipoic acid (α‐LA) has
a strong antioxidant capacity, but the effect of α‐LA on parthenogenetic activation of oocytes …

Materials and Methods: Thirty rats were equally divided into Groups I, II, III, IV, and V. Group I
was normal control, wherein the rats were fed with normal feed and water ad libitum. Group …

Objective. This study aims to evaluate whether alpha‐lipoic acid and/or coenzyme Q10 can
protect the prepubertal ovarian tissue from ischemia‐reperfusion injury in an experimental …

Cyclic nucleotide phosphodiesterases (PDEs) are group of enzymes responsible for the
hydrolysis of cyclic adenosine 3′, 5′ monophosphate (cAMP) and cyclic guanosine 3 …