International Union of Pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and …
RT Jensen, JF Battey, ER Spindel, RV Benya - Pharmacological reviews, 2008 - ASPET
The mammalian bombesin receptor family comprises three G protein-coupled heptahelical
receptors: the neuromedin B (NMB) receptor (BB1), the gastrin-releasing peptide (GRP) …
receptors: the neuromedin B (NMB) receptor (BB1), the gastrin-releasing peptide (GRP) …
Arsenic trioxide: insights into its evolution to an anticancer agent
Arsenic and its various forms have been in use in ancient Chinese medicine for more than
2000 years. Arsenicals have gained importance for having remedial effects for various …
2000 years. Arsenicals have gained importance for having remedial effects for various …
Targeted delivery of multifunctional magnetic nanoparticles
JR McCarthy, KA Kelly, EY Sun, R Weissleder - Nanomedicine, 2007 - Taylor & Francis
Magnetic nanoparticles and their magnetofluorescent analogues have become important
tools for in vivo imaging using magnetic resonance imaging and fluorescent optical …
tools for in vivo imaging using magnetic resonance imaging and fluorescent optical …
Characteristics of cell lines established from human gastric carcinoma
JG Park, H Frucht, RV LaRocca, DP Bliss Jr, Y Kurita… - Cancer research, 1990 - AACR
We report the establishment and characterization of four continuous cell lines derived from
human primary and metastatic gastric carcinomas, and we compare their properties with a …
human primary and metastatic gastric carcinomas, and we compare their properties with a …
[99mTc]Demobesin 1, a novel potent bombesin analogue for GRP receptor-targeted tumour imaging
B Nock, A Nikolopoulou, E Chiotellis, G Loudos… - European journal of …, 2003 - Springer
Demobesin 1 is a potent new GRP-R-selective bombesin (BN) analogue containing an open
chain tetraamine chelator for stable technetium-99m binding. Following a convenient …
chain tetraamine chelator for stable technetium-99m binding. Following a convenient …
Non-invasive quantification of the beta cell mass by SPECT with 111In-labelled exendin
M Brom, W Woliner-Van Der Weg, L Joosten, C Frielink… - Diabetologia, 2014 - Springer
Aims/hypothesis A reliable method for in vivo quantification of pancreatic beta cell mass
(BCM) could lead to further insight into the pathophysiology of diabetes. The glucagon-like …
(BCM) could lead to further insight into the pathophysiology of diabetes. The glucagon-like …
High levels of intracellular bombesin characterize human small-cell lung carcinoma
" Small cells" or" oat cells" characterize a virulent form of lung cancer and share many
biochemical properties with peptide-secreting neurones. The neuropeptide bombesin is …
biochemical properties with peptide-secreting neurones. The neuropeptide bombesin is …
cDNA cloning, characterization, and brain region-specific expression of a neuromedin-B-preferring bombesin receptor
E Wada, J Way, H Shapira, K Kusano… - Neuron, 1991 - cell.com
Recent binding studies in the central nervous system and other tissues provide evidence
that the mammalian bombesin-like peptides, gastrin-releasing peptide (CRP) and …
that the mammalian bombesin-like peptides, gastrin-releasing peptide (CRP) and …
Imaging the distribution of gastrin-releasing peptide receptors in cancer
Targeting tumor-expressed receptors using selective molecules for diagnostic, therapeutic,
or both diagnostic and therapeutic (theragnostic) purposes is a promising approach in …
or both diagnostic and therapeutic (theragnostic) purposes is a promising approach in …
Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells.
E Rozengurt, J Sinnett-Smith - Proceedings of the National …, 1983 - National Acad Sciences
Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. At nanomolar concentrations
the peptide markedly enhances the ability of fresh serum to stimulate DNA synthesis in …
the peptide markedly enhances the ability of fresh serum to stimulate DNA synthesis in …