International Union of Pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and …

RT Jensen, JF Battey, ER Spindel, RV Benya - Pharmacological reviews, 2008 - ASPET
The mammalian bombesin receptor family comprises three G protein-coupled heptahelical
receptors: the neuromedin B (NMB) receptor (BB1), the gastrin-releasing peptide (GRP) …

Arsenic trioxide: insights into its evolution to an anticancer agent

M Hoonjan, V Jadhav, P Bhatt - JBIC Journal of Biological Inorganic …, 2018 - Springer
Arsenic and its various forms have been in use in ancient Chinese medicine for more than
2000 years. Arsenicals have gained importance for having remedial effects for various …

Targeted delivery of multifunctional magnetic nanoparticles

JR McCarthy, KA Kelly, EY Sun, R Weissleder - Nanomedicine, 2007 - Taylor & Francis
Magnetic nanoparticles and their magnetofluorescent analogues have become important
tools for in vivo imaging using magnetic resonance imaging and fluorescent optical …

Characteristics of cell lines established from human gastric carcinoma

JG Park, H Frucht, RV LaRocca, DP Bliss Jr, Y Kurita… - Cancer research, 1990 - AACR
We report the establishment and characterization of four continuous cell lines derived from
human primary and metastatic gastric carcinomas, and we compare their properties with a …

[99mTc]Demobesin 1, a novel potent bombesin analogue for GRP receptor-targeted tumour imaging

B Nock, A Nikolopoulou, E Chiotellis, G Loudos… - European journal of …, 2003 - Springer
Demobesin 1 is a potent new GRP-R-selective bombesin (BN) analogue containing an open
chain tetraamine chelator for stable technetium-99m binding. Following a convenient …

Non-invasive quantification of the beta cell mass by SPECT with 111In-labelled exendin

M Brom, W Woliner-Van Der Weg, L Joosten, C Frielink… - Diabetologia, 2014 - Springer
Aims/hypothesis A reliable method for in vivo quantification of pancreatic beta cell mass
(BCM) could lead to further insight into the pathophysiology of diabetes. The glucagon-like …

High levels of intracellular bombesin characterize human small-cell lung carcinoma

TW Moody, CB Pert, AF Gazdar, DN Carney, JD Minna - Science, 1981 - science.org
" Small cells" or" oat cells" characterize a virulent form of lung cancer and share many
biochemical properties with peptide-secreting neurones. The neuropeptide bombesin is …

cDNA cloning, characterization, and brain region-specific expression of a neuromedin-B-preferring bombesin receptor

E Wada, J Way, H Shapira, K Kusano… - Neuron, 1991 - cell.com
Recent binding studies in the central nervous system and other tissues provide evidence
that the mammalian bombesin-like peptides, gastrin-releasing peptide (CRP) and …

Imaging the distribution of gastrin-releasing peptide receptors in cancer

L Baratto, H Duan, H Mäcke… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Targeting tumor-expressed receptors using selective molecules for diagnostic, therapeutic,
or both diagnostic and therapeutic (theragnostic) purposes is a promising approach in …

Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells.

E Rozengurt, J Sinnett-Smith - Proceedings of the National …, 1983 - National Acad Sciences
Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. At nanomolar concentrations
the peptide markedly enhances the ability of fresh serum to stimulate DNA synthesis in …