Endocrine disrupting chemicals: effects on endocrine glands

R Lauretta, A Sansone, M Sansone… - Frontiers in …, 2019 - frontiersin.org
In recent years, endocrine disrupting chemicals have gained interest in human
physiopathology and more and more studies aimed to explain how these chemicals …

[HTML][HTML] Emerging roles of bile acids in mucosal immunity and inflammation

ML Chen, K Takeda, MS Sundrud - Mucosal Immunology, 2019 - Elsevier
Bile acids are cholesterol-derived surfactants that circulate actively between the liver and
ileum and that are classically recognized for emulsifying dietary lipids to facilitate absorption …

Polychlorinated biphenyls (PCBs) in the environment: Recent updates on sampling, pretreatment, cleanup technologies and their analysis

AVB Reddy, M Moniruzzaman… - Chemical Engineering …, 2019 - Elsevier
Polychlorinated biphenyls (PCBs) are a class of synthetic organic compounds containing
carbon, hydrogen and chlorine atoms. They have been used in various industrial and …

Xenobiotic metabolism and transport in Caenorhabditis elegans

JH Hartman, SJ Widmayer… - Journal of Toxicology …, 2021 - Taylor & Francis
Caenorhabditis elegans has emerged as a major model in biomedical and environmental
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …

Host–microbiome interactions: the aryl hydrocarbon receptor as a critical node in tryptophan metabolites to brain signaling

N Ma, T He, LJ Johnston, X Ma - Gut microbes, 2020 - Taylor & Francis
Tryptophan (Trp) is not only a nutrient enhancer but also has systemic effects. Trp
metabolites signaling through the well-known aryl hydrocarbon receptor (AhR) constitute the …

Engineering strategies in microorganisms for the enhanced production of squalene: advances, challenges and opportunities

N Gohil, G Bhattacharjee, K Khambhati… - … in bioengineering and …, 2019 - frontiersin.org
The triterpene squalene is a natural compound that has demonstrated an extraordinary
diversity of uses in pharmaceutical, nutraceutical, and personal care industries. Emboldened …

Diversity as opportunity: insights from 600 million years of AHR evolution

ME Hahn, SI Karchner, RR Merson - Current opinion in toxicology, 2017 - Elsevier
The aryl hydrocarbon receptor (AHR) was for many years of interest only to pharmacologists
and toxicologists. However, this protein has fundamental roles in biology that are being …

Tetraspanin assemblies in virus infection

L Florin, T Lang - Frontiers in immunology, 2018 - frontiersin.org
Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma
membrane “master organizers.” They form Tspan-enriched microdomains (TEMs or TERMs) …

[图书][B] Encyclopedia of molecular pharmacology

S Offermanns, W Rosenthal - 2021 - Springer
Antioxidants are molecules characterized by function rather than common structural motifs.
Their common feature is the capability of acting “anti”-oxidants in biological systems. Owing …

In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction …

P Šimečková, K Pěnčíková, O Kováč, J Slavík… - Science of The Total …, 2022 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) may interact with multiple intracellular receptors
and related signaling pathways. We comprehensively evaluated the toxicity profiles of six …